What are the responsibilities and job description for the Associate Scientist, Large Molecule CMC Analytical Development position at Denali Therapeutics Inc?
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Key Accountabilities/Core Job Responsibilities:
Assist in the development of chromatography, electrophoresis, spectroscopy and mass spectrometry based analytical methods to be used for product release, stability, and characterization testing.
Perform timely analytical testing that enables bioprocess and formulation development.
Contribute to the design and execution of experiments for demonstrating method robustness and performance.
Critically evaluate analytical data to support method development decisions and product quality comparisons.
Accurately and thoroughly document experiments in ELN.
Summarize and present data in a clear and meaningful way.
Author and review analytical test methods and development reports.
Qualifications/Skills:
B.S. or M.S. in Analytical Chemistry, Biochemistry, Chemical Engineering, Biotechnology or related scientific discipline with a minimum of 2 years of CMC analytical development experience in biotech/pharma.
Hands-on experience with various analytical methods for biologics and residual process impurities (i.e. chromatography, capillary electrophoresis, spectroscopy, LC-MS, etc.)
Excellent laboratory, critical thinking, scientific problem-solving, and organizational skills.
Familiarity with applicable GMP requirements.
Knowledge of statistical approaches for data interpretation and analytical method development.
Motivated, detail-oriented, naturally curious individual with a creative approach to scientific problem solving.
Excellent spoken and written communication skills.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
Salary : $107,000 - $130,000
