What are the responsibilities and job description for the Automation and Assay Research Scientist position at Eagle Health, LLC?
Job Description:
Job Requirements:
Automation and Assay Research Scientist
Work Location: Fort Detrick, MD
Eagle Health is seeking an Automation and Assay Research Scientist to join our team in Fort Detrick, MD.
Core Duties:
- Provide Robotic Liquid Handling Automation support for research efforts of the Therapeutics Development Center (TDC). Support will be required mainly in BSL-2 environment with subsequent potential support in BSL-3, and BSL-4 environments. Thus, it will require enrollment in the Biological Personnel Reliability Program (BPRP) program
- conduct basic and applied research on current and emerging threats in support of the BD and infectious disease program
- Aid in the execution of scientific studies–throughput screening assays, enzymatic assays, collection/data analysis, and maintain the laboratory and respective laboratory equipment
- Assist in the development, execution, and evaluation of high-throughput in vitro screening projects for the antibacterial, anti-viral, and anti-toxin therapeutic areas and assist in the development of novel assays/methods for various programs
- Assist in screening of molecular compound libraries for therapeutic efficacy to support Medical Countermeasures (MCM) development
- Perform compound treatment to evaluate therapeutic small molecules for enzymatic/ antibacterial/ antiviral/antitoxin activity. In vitro assays include enzymatic assays, cell-based phenotypic and reporter assays, Minimum Inhibitory Concentration (MIC), and plaque assays
- Required to write new workflows associated with the automation instruments in support of any new high-throughput screening assay and may include combination studies and similar
- Assist in data analysis using Spotfire and Genedata
- Perform basic molecular biology techniques to support creation of novel cell or enzymatic based assays for evaluation of MCM
- Assist in the preparation of technical reports, standard operating procedures, and manuscripts relating to their research efforts and may be expected to present research findings at one scientific conference per year and will present results in written and oral format publicly and internally as requested
- Responsible for assessing and maintaining all the robotic instruments and associated laboratory supplies, assessing supplies and ensuring supply orders are coordinated with Division resources, and ensure that all assigned laboratory space is orderly and compliant with all applicable regulatory guidance
- Prepare and provide technical point of contact (TPOC) a Therapeutic Screening Scientific Research Technical progress report no later than (NLT) the last day of each month
- Contractor shall present research findings/presentations at monthly lab meetings and attend scientific discussion weekly meetings
- BPRP enrollment is required and will be held and maintained IAW the provisions in this contract and all applicable regulations
Job Requirements:
Requirements:
- Proficient in using automated liquid handling systems such as Beckman Biomek, Perkin Elmer Janus, Viaflo, Viafill, Multi-drop Combi, and HP dispensers
- Familiarity with handling of therapeutic small molecules and compound management
- Experience in setting up in vitro enzymatic assays such as kinases, proteases, and similar
- Must be a U.S. citizen with a valid U.S. passport
- Must have authorization to work in the United States as defined by the Immigration Reform Act of 1986
