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Advisor - Upstream Process Development

Eli Lilly and Company
Indianapolis, IN Full Time
POSTED ON 2/27/2025
AVAILABLE BEFORE 5/28/2025

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

121,500 - $198,000

Organization Overview

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism

This position is part of the Upstream Process Development group in the Bioprocess Research and Development (BR&D) organization within Lilly Research Labs. BR&D delivers new medicines to patients through the development and commercialization of insulins, peptides, oligonucleotides, monoclonal antibodies, novel therapeutic proteins, and gene therapy systems.

The Advisor - Upstream Process Development is responsible for the development and optimization of cell lines, strains, technology and processes for production of recombinant therapeutic proteins and genetic medicines, as well as for process control strategy development, process scale-up and technology transfer to pilot plant and manufacturing sites

Responsibilities :

  • Lead the design, execution, and interpretation of upstream experiments for processes leading to the generation of drug substance (therapeutic proteins or genetic medicines).
  • Participate in and / or lead cross-functional process development teams, and effectively collaborate with other groups in Bioprocess and Bioproduct Development, Discovery, TS&MS and Manufacturing.
  • Support transfer of upstream processes to manufacturing sites.
  • Use mathematical methods and computer tools to model and explore experimental systems.
  • Authorship of technical reports and regulatory documents.
  • Work effectively with external parties on development projects, research collaborations and outsourcing efforts.
  • Lead / support implementation of organizational strategic initiatives in support of the Lily pipeline.
  • Keep abreast of relevant scientific literature / new technologies / capabilities and regulatory initiatives / requirements. Lead implementation, as appropriate.
  • Leverage internal and external influence to solve problems and benchmark potential solutions.
  • Leading / supporting organizational strategic initiatives, evaluating and / or installing new capabilities / technologies and leveraging internal and external influence to solve problems and benchmark potential solutions.
  • Provide coaching, training, and administration of performance management to personnel (primarily, but not limited to, direct reports).
  • Ensure work and team activities are aligned with all relevant Development Quality, regulatory, HSE, GLP and requirements.

Basic Requirements :

  • Ph.D. in Chemical Engineering, Biochemistry, Biology, Bioengineering or related field; alternatively, skills commensurate with a PhD scientist with 0-3 years of experience.
  • General knowledge of cell culture, molecular biology and fermentation with an emphasis on production of recombinant proteins and genetic medicines.
  • Additional Skills / Preferences :

  • General knowledge and understanding of issues associated with scaling of upstream processes, and use of statistics for data analysis
  • Cell culture experience with CHO or HEK293 cell lines.
  • Problem solving and decision-making.
  • Demonstration of scientific and people leadership skills.
  • Effective oral and written communication skills.
  • Must be able to work productively in an interdisciplinary team environment.
  • Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https : / / careers.lilly.com / us / en / workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

    Lilly is an EEO / Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

    Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include : Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

    Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and / or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

    WeAreLilly

    Salary : $121,500 - $198,000

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