What are the responsibilities and job description for the In Vitro Pharmacologist, Obesity Research - Boston position at Eli Lilly and Company?
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is
$69,000 - $179,300
The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule, and genetic therapeutics for the treatment of diabetes, obesity, and associated complications.
We are seeking a skilled, motivated, and versatile individual who can help to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The ideal candidate will have a strong background in cell culture and cell-based functional assays, playing a crucial role in supporting our comprehensive discovery efforts and ongoing pipeline projects focused on anti-obesity therapeutics. In this position, the candidate will assist in assay development and conduct established assays to validate new targets and/or characterize the in vitro function of novel therapeutics. Additionally, the candidate will be responsible for establishing critical laboratory capabilities and collaborating with other scientists within and across departments to achieve both project and departmental goals.
Interested in engaging with groundbreaking science? Apply now to become a part of the Lilly Team!
Key Position Requirements/responsibilities Include
Technical/scientific skills. Expertise in the following is a must-have:
Experience/expertise with the following is a plus:
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is
$69,000 - $179,300
The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule, and genetic therapeutics for the treatment of diabetes, obesity, and associated complications.
We are seeking a skilled, motivated, and versatile individual who can help to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The ideal candidate will have a strong background in cell culture and cell-based functional assays, playing a crucial role in supporting our comprehensive discovery efforts and ongoing pipeline projects focused on anti-obesity therapeutics. In this position, the candidate will assist in assay development and conduct established assays to validate new targets and/or characterize the in vitro function of novel therapeutics. Additionally, the candidate will be responsible for establishing critical laboratory capabilities and collaborating with other scientists within and across departments to achieve both project and departmental goals.
Interested in engaging with groundbreaking science? Apply now to become a part of the Lilly Team!
Key Position Requirements/responsibilities Include
Technical/scientific skills. Expertise in the following is a must-have:
- Aseptic cell culture techniques with mammalian cells.
- Transient transfections and generation of stable cell lines.
- Development of cell-based functional assays or biochemical assays and screening of novel therapeutics in 96-/384-well plate formats at a single concentration or in a concentration/response manner.
- Knowledge of basic pharmacology (e.g. concentration/response curves, determination of binding affinity, potency, Hill’s slope and in vitro efficacy). Mechanism of action studies of drugs.
- Experience with colorimetric, luminescence and fluorescence-based readouts, including HTRF. Proficient in operating plate readers, liquid handling robots and assay automation.
- Gene expression studies by qPCR, western blot and FACS techniques.
- Proficient oral and written communication skills and ability to work both independently and in teams.
- Requirement for accurate record keeping and independent data analysis. Will perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.
- Attention to detail and ability to prioritize work on multiple projects, timelines and company goals.
- Eager to grasp fundamental principles, swiftly acquire new abilities, and adjust to novel challenges.
- B.S. and/or M.S. in biology, pharmacology, biochemistry or related field.
- 5 years of laboratory experience (5-10 years industry experience preferred)
Experience/expertise with the following is a plus:
- Native cell lines and primary cell cultures, iPSCs, co-cultures, 3D cultures.
- Exposure to multiple therapeutic target classes (e.g. membrane receptors, including G-Protein Coupled Receptors or GPCRs, enzymes, transporters, etc.) and multiple modalities (small molecules, peptides, antibodies, siRNAs, etc.).
- Experience with ELISA assays.
- Working knowledge or background in cardiometabolic diseases.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Salary : $69,000 - $179,300
