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Research Scientist -ASCVD and Obesity

Eli Lilly
Indianapolis, IN Full Time
POSTED ON 1/25/2025
AVAILABLE BEFORE 4/24/2025

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is

63,000 - $162,800

The Lilly Diabetes, Obesity, and Complications Therapeutic Area has created a research team focused on discovery and preclinical development of new therapeutics for the treatment of Atherosclerotic Cardiovascular Disease (ASCVD) and Obesity. The team is looking for an experienced in vitro biologist to develop, validate and conduct in vitro and cell-based pharmacology assays for drug discovery projects. The candidate should have a proven track record in the implementation of in vitro assays and be able to consistently follow detailed protocols and provide critical and thorough data evaluation. The candidate is expected to work in collaboration with the ASCVD, Obesity, and Incretin Discovery groups in a team-oriented environment and to support other groups when expertise as needed.

  • Design, validate and implement in vitro assays for novel therapeutics.
  • Apply state of the art automation to enable compound screening in 384-well assay format or greater, experience with multidrop liquid dispenser, echo liquid handler, is preferred.
  • Critically evaluate data using NGR data analysis software.
  • Perform cell culturing and process tissues collected from animal studies. Use molecular biology / biochemistry techniques, including nucleic acid transfection, stable or transient cell line generation and evaluation, and gene expression profiling (qPCR).
  • Develop and perform assays in the area of receptor pharmacology including receptor binding, and functional cellular readouts, such as cAMP, phosphorylation, calcium and other biomarkers and molecular biology techniques such as ELISA, SDS-PAGE and Western blotting.
  • Accurate record keeping, independent data analysis, and reporting of data in written and oral formats. Perform work in full compliance with Lilly Research Policies, and complete all required training activities in the timeframe specified.
  • Ability to be pro-active, flexible, and capable of independent trouble shooting and problem solving. Work within a team-oriented lab environment and work within cross-functional project teams.

Basic Qualifications

Undergraduate or Masters degree in biology or a closely related field

Additional Skills / Preferences

  • Experience and willingness to work with radioisotopes, chemical, and biological hazards.
  • Experience in diabetes and / or metabolic diseases is preferred.
  • Proven ability to work in flexible, team-oriented environment.
  • Oral / written communication / listening skills in English are essential.
  • Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https : / / careers.lilly.com / us / en / workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

    Lilly is an EEO / Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

    Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include : Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

    Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and / or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

    WeAreLilly

    Salary : $63,000 - $162,800

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