Demo

Associate Director, DMPK

Enigma Search
San Mateo, CA Full Time
POSTED ON 1/17/2025
AVAILABLE BEFORE 4/15/2025

Position Description :

The AD, Drug Metabolism and Pharmacokinetics or (DMPK) role provides an opportunity to influence the DMPK strategy and support the development of innovative therapeutics. Initially focused as an individual contributor, this position will require close collaboration with external partners such as Pharma and Contract Research Organizations (CROs). With the company’s growth, potential exists for this role to transition into a leadership position with direct reports.

Role :

  • Strategic Leadership :
  • Develop and implement the DMPK strategy to support drug discovery and development programs.
  • Provide expert DMPK guidance and input to project teams.
  • Represent the DMPK function in cross-functional meetings and interactions with external stakeholders.
  • Stay updated on the latest advancements in DMPK science and regulatory guidelines.
  • Collaboration and Outsourcing :
  • Collaborate effectively with CROs and other external partners to execute DMPK studies.
  • Manage relationships with CROs, including study design, data analysis, and report writing.
  • Oversee the quality and timely delivery of DMPK data from external partners.
  • Individual Contribution :
  • Design and execute DMPK studies, encompassing in vitro and in vivo experiments.
  • Analyze and interpret DMPK data to support drug candidate selection and development.
  • Author and review DMPK reports, regulatory documents, and scientific publications.

Nice To Have :

  • Experience with various therapeutic modalities, including small molecules, biologics, and oligonucleotides.
  • Experience with modeling and simulation software.
  • Familiarity with regulatory guidelines and requirements for DMPK studies.
  • Position Requirements :

  • Ph.D. in pharmacokinetics, drug metabolism, or a related field.
  • 8 years of experience in DMPK within the pharmaceutical or biotechnology industry.
  • Strong understanding of DMPK principles and their application to drug discovery and development.
  • Extensive experience in designing and conducting in vitro and in vivo DMPK studies.
  • Proven ability to analyze and interpret DMPK data to inform drug development decisions.
  • Experience in managing CROs and external partnerships.
  • Prior experience in writing regulatory documents is highly desirable.
  • Must be willing to work onsite at least 4 days a week.
  • Compensation :

    The estimated base salary range for this role is $234,000 - $242,000, with actual pay based on various factors including experience

    Salary : $234,000 - $242,000

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