What are the responsibilities and job description for the PRINCIPAL RESEARCH ASSOCIATE, FORMULATION CHEMISTRY (CONTRACT) position at Entrada Therapeutics?
The Organization
What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.
Our Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.
Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.
We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.
The Perfect Addition to Our Team
You are a highly motivated and dependable Principal Research Associate who thrives in a collaborative and fast-paced environment. You have a team player mentality and excellent communication skills that will allow you to collaborate effectively as you work alongside your team, as well as cross-functionally within the organization. You are oriented and highly versatile in high-throughput formulations.
The Opportunity
The Principal Research Associate will report to the Senior Scientist, Discovery Chemistry, and be responsible for the formulation and characterization of oligonucleotides, peptides, conjugates, and other novel molecules. You will manage the chemical inventory and maintain a good experimental record in electronic lab notebooks. The ideal candidate will interpret and present research data and findings in internal scientific meetings as well as prepare procedures and technical reports.
Responsibilities
- Formulate oligonucleotides, peptides, conjugates, and other novel molecules for in vitro and in vivo studies to support DM1 and other discovery projects.
- Coordinate with internal stakeholders to ensure that materials are available for maintaining the project timeline.
- Review formulation characterization results to meet sample release criteria.
- Troubleshoot experiments when problems arise.
- Coordinate with cross-functional teams for data and sample transfers.
- Organize and document all experimental data and connect with all related in vitro and in vivo.
The Necessities
At Entrada, our passion for science, our devotion to patients and our values drives our behavior :
To thrive on our team, you will need to come with :
The Perks
By becoming a team member here at Entrada, you'll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.
Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies
Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters / agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters / agencies do not constitute any type of relationship between the recruiter / agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.
Privacy Statement
Entrada Therapeutics, Inc. (the Entrada , we, us, or our ) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.
