Demo

Lipid Nanoparticle Process Development Scientist

Eurofins GSC Poland Sp. z o. o.
Boston, MA Full Time
POSTED ON 1/14/2025
AVAILABLE BEFORE 4/6/2025

The candidate will have a highly visible and integral role towards the process development, scale-up, and manufacturing of Gene Therapy LNPs. The ideal candidate will have experience with lipid nanoparticle formulation, various mixing equipment, TFF system, characterization tools and understanding / knowledge of process parameters. In this highly collaborative and cross-functional role, you will help develop / optimize the client process and improve process understanding for multiple programs at various stages of non-clinical development.

The full job description covers all associated skills, previous experience, and any qualifications that applicants are expected to have.

Job Responsibilities

  • Support scale-up development and optimization of LNP drug product formulation processes and storage form development for gene therapies.
  • Provide formulation support for non-GLP large animal studies.
  • Work with cross-functional teams to support process transfer, scale-up, and resolving process troubleshooting.
  • Formulate and characterize LNPs for preclinical studies internal and external to support consistency and high-quality readout across batches and stability evaluations.
  • Maintain records of all relevant data in the electronic laboratory notebook system, hard cover recording (batch record) and present findings to client project teams.
  • Contribute SOP, batch records, report, campaign summary reports, etc.
  • Other duties as assigned.

Minimum Qualifications

  • Master’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 2 years of relevant industrial working experience preferred. Alternatively, a bachelor’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 4 years of recent relevant industrial working experience.
  • Experience in LNP formulation (NanoAssemblr) and nanoparticle characterization.
  • Understanding engineering of process development, scale-up, manufacturing, and tech transfer.
  • Experience with analytical methods (DLS, UV / VIS, Osmo, pH, etc.) for LNP characterization.
  • Experience with large-scale LNP formulation (T-mixing, IJM) and TFF processes.
  • Authorization to work in the United States indefinitely without restriction or sponsorship.
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