What are the responsibilities and job description for the SRA / Assoc Scientist / Scientist, Biotherapeutics position at EVOLVEIMMUNE THERAPEUTICS INC?
Job Description
Job Description
Who We Are
EvolveImmune Therapeutics is a next-generation immunotherapy company pioneering a new class of precision cancer medicines to transform patient outcomes, compared to current solid tumor therapies. Our first-in-category biotherapeutic EVOLVE platform utilizes integrated T cell co-stimulation to directly target tumor cells to deliver durable, tissue-localized anti-tumor adaptive immune responses. Our newly expanded, state-of-the-art 16,000 square foot laboratory and office space located in the New Haven, CT biotechnology corridor and our laboratory footprint in Farmington, CT support in-house biologics, immunobiology, and translational activities, enabling our rapid pipeline progress. This includes EV-104, our lead solid tumor program rapidly advancing toward IND filing.
The Role
We are seeking a highly motivated and skilled Scientist to join our dynamic Biotherapeutics team and contribute to the characterization and development of our next-generation immuno-oncology pipeline. This role will focus on utilizing LC-MS, biochemical and biophysical methods to analyze and characterize the structural integrity, functionality, and stability of these innovative molecules.
Key Responsibilities
- Develop and execute LC-MS workflows for biotherapeutics characterization, including intact and subunit mass analysis, peptide mapping, glycan profiling, and post-translational modification analysis.
- Perform analytical, biochemical, and biophysical assays using techniques such as SEC, HIC, DSC, ELISA, SPR, and BLI to assess purity, stability, aggregation propensity, and target binding kinetics and affinity.
- Collaborate effectively with cross-functional teams to ensure alignment of project goals and deliver accurate and timely results.
- Analyze and interpret experimental data to draw meaningful conclusions, present findings and recommendations to team and management.
- Address and resolve technical challenges related to LC-MS instrumentation and data analysis.
- Stay current with advancement in LC-MS and biophysical techniques, implementing innovative approaches where applicable, contribute to scientific publications.
Qualifications
Preferred Qualifications
EvolveImmune Therapeutics requires all employees to be fully vaccinated against COVID-19. You may seek reasonable accommodations for medical and religious reasons. However, your application is no guarantee that such accommodations will be made available.
EvolveImmune provides a competitive compensation and benefits package.
EvolveImmune Therapeutics, Inc. is an equal opportunity employer.
