Senior Scientist II, Media Development

Just-Evotec is seeking a scientific leader in cell culture media development who is passionate about expanding worldwide access to biotherapeutics through the advancement of continuous bioprocessing technology and mammalian cell culture processes. This person will join a fast-paced, collaborative team to build new Just-Evotec media services for the advancement of low-cost biotherapeutics manufacturing technology. The position requires a strong background in mammalian cell culture media development, experience in process development of therapeutic proteins, and demonstrated leadership capabilities in leading a small team of early career scientists. A proven track record of successfully implementing novel (non-off-the-shelf) cell culture media formulations in biotherapeutics production is required; experience with using LC-MS-based metabolomics data sets towards developing novel cell culture formulations is preferred. Strong written and verbal communication skills, including the ability to communicate effectively over teleconference and web-based meetings are necessary. The ideal candidate is curious, creative, engaged, and constantly looking for ways to advance and intensify scientific processes, streamline workflows, and improve technology.

Responsibilities

• With input from diverse stakeholders, independently lead media optimization efforts to develop novel workflows for increasing titer, cell viability, and product quality targets throughout long-duration upstream processes.
• Serve as a technical resource and represent the Media function on early- and late-stage cross-functional development teams
• Transfer novel media formulations to Manufacturing, support large-scale GMP media preparation protocols and deviations
• Author CMC regulatory sections as required
• Drive advancement of the Just – Evotec upstream platform and incorporate novel technologies to characterize and model cell cultures
• Develop strategy for implementing new platform media analysis methods into experimental workflows for client services.
  
  

Qualifications

• BS in Cell Biology, Engineering, Biochemistry, or related field and 12 years industry experience or PhD with 5 years relevant experience
• Subject Matter Expert (SME) level understanding of cell biology, cell culture media development, and related analytical equipment. Perfusion technology experience is preferred.
• Experience with DOE and statistical analysis, experience analyzing data using tools such as JMP, R, or Python. Experience with training machine learning models for optimizing high dimensional data sets preferred.
• Experience with high throughput cell culture (e.g. deep-well plate assays, robotics systems such as Ambr)
• Enthusiastic problem-solver
• Management experience leading a 1-2 person early career scientist team.
• Proven track record developing novel media formulations for cell culture programs beyond initial off-the-shelf cell culture media screening. Experience using omics-based approaches to drive towards novel cell culture media formulations is preferred.
• Technical leader is spent media analysis for optimizing cell culture media and feeds. Experience with flux balance analysis preferred.
• Strong written and verbal technical communication skills
• Self-motivated, able to make and follow through on goals
• Action-oriented, flexible, and eager to learn and grow skill sets
• Able to stay organized and relaxed in complex situations, keep track of multiple tasks and data
• Experience with Microsoft Office apps (Word, PowerPoint, Excel)
• Experience with commercial process development, process characterization, and validation preferred
  
  

The base pay range for this position at commencement of employment is expected to be $120,000-$140,000; Base salary offered may vary depending on individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.

Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.