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Clinical Operations Therapeutic Area Leader- Hematology

F. Hoffmann-La Roche AG
San Francisco, CA Full Time
POSTED ON 1/20/2025
AVAILABLE BEFORE 4/18/2025

Clinical Operations Therapeutic Area Leader- Hematology

Apply below after reading through all the details and supporting information regarding this job opportunity.

Locations : South San Francisco, Mississauga, Welwyn, Basel

Time Type : Full-time

Posted On : Yesterday

Job Requisition ID : 202411-130453

The Position

At Roche / Genentech Pharma Product Development Global Clinical Operations (PDG), we are determined to transform drug development and realize our Pharma Ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2029. We are looking for a Clinical Operations Therapeutic Area Leader to lead and drive the delivery of our Oncology-Hematology Portfolio. This senior leadership position holds significant accountability for clinical operations strategy and execution as well as enterprise collaboration.

PD’s mission is to improve patients’ lives around the world through unique medicines that have a meaningful impact. Cross-functionally we conduct global clinical trials, analyze results, monitor safety, and work with regulatory authorities to provide truly differentiated medicines to patients. Our primary therapeutic focus areas are Oncology, Hematology, Neurology, Immunology, Ophthalmology, Cardiovascular, Renal, and Metabolism.

The Opportunity :

The Oncology-Hematology Clinical Operations Therapeutic Area Leader in PDG at Roche / Genentech is responsible and accountable for the strategy and delivery of the PD portfolio of programs and studies in Oncology-Hematology. As the Oncology-Hematology Therapeutic Area Leader, you will :

  • Develop and Evolve Oncology-Hematology Portfolio Strategy : Accountable for the overall PD clinical operations strategy for the Oncology-Hematology portfolio. Continuously refine the strategy in response to the evolving landscape to ensure clinical trial delivery aligns with the Clinical Development Plan (CDP) and One Pharma Strategy.
  • Oversight and Risk Mitigation for Portfolio Delivery : Maintain active oversight of asset and study delivery to monitor portfolio status, proactively identify risks, and implement mitigation strategies to ensure seamless execution of clinical trials.
  • Strategic Stakeholder Alignment and Collaboration : Drive alignment among cross-functional stakeholders, including PDG, APO, COEs, early and late-stage development teams, and enterprise leaders. Act as a key operational voice influencing decision-making and optimizing portfolio delivery.
  • Operational Leadership and Innovation : Leverage analytics, portfolio optimization expertise, and innovative approaches to accelerate clinical trial delivery, improve efficiency and quality, manage budgets, enhance probability of technical success (PTS), and ensure a patient- and site-centric approach, including fostering inclusive research.
  • Representation and Influence Across Roche Enterprise : Serve as the PDG voice in the Oncology-Hematology therapeutic areas, building and maintaining collaborative relationships with senior leaders across Roche and external partners, such as health authorities, patient advocacy groups, and vendors.
  • Leadership and Team Development : Lead and develop a matrixed organization of ~150 employees, including 10-12 direct reports. Foster a culture of collaboration, inclusivity, high performance, and alignment with Roche’s leadership principles. Champion diversity, equity, and inclusion (DE&I) to build an empowered and diverse talent pipeline.
  • Collective Leadership with an Enterprise Mindset : Represent Oncology-Hematology as part of the Portfolio Delivery Leadership Team. Demonstrate collective leadership to serve the broader PDG and PD organization while focusing on patient, site, and enterprise objectives.
  • People Management and Administrative Oversight : Drive engagement, provide regular performance feedback, and manage administrative responsibilities related to team operations, including Workday tasks and addressing employment-related matters.

Who You Are :

  • 15 years pharmaceutical clinical operations experience with at least 10 years in global clinical operations strategy leadership. Additional commercial or relevant experience is considered an asset.
  • Strong knowledge in the area of Oncology / Hematology including external trends and issues in the global Oncology-Hematology landscape, and development and delivery of large endpoint-driven clinical trials.
  • Comprehensive understanding of global pharma clinical development in international settings.
  • Proven success in strategy development and execution using analytics, data-driven decision-making, and a track record of expanding access to underserved populations while meeting or exceeding ambitious goals.
  • Experience managing large, matrixed organizations, including leading direct reports and people leaders, recruiting and developing high-performing teams, and fostering collaboration and trust with stakeholders.
  • Fluency in English with additional language skills as an asset, and flexibility for frequent national or international travel based on business needs.
  • This position can be located at the Basel, Switzerland; South San Francisco, United States; Welwyn, England; or Mississauga, Canada HQ sites. Expectation of ongoing and sustained campus presence at the site in compliance with local requirements.

    Relocation benefits are available for this posting.

    The expected salary range for this position based on the primary location of California is $227,600 - $422,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This position also qualifies for the benefits detailed at the link provided below.

    Who We Are

    A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer and other serious illnesses.

    Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought, and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve.

    Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status.

    If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

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    Salary : $227,600 - $422,600

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