What are the responsibilities and job description for the Research Scientist Intern, Immuno Oncology position at FIG Therapeutics, Inc.?
Company Description
FIG (Factor Induced Gene)Therapeutics, Inc. is an early stage biotech company developing a proprietary polynucleotide-based therapeutic that hijacks machinery specific to cancer cells to drive a multimodal immunotherapy that both recruits anti-tumor immune cells and inhibits drivers of the immunosuppressive tumor microenvironment. Essentially, we turn cancer against itself.
Role Description
This is a paid 3-month internship role ($16-20/hr) with the goal of conversion to full time role with good performance. Exceptional candidates may even have the opportunity to become a co-founder. The ideal candidate is a passionate recent PhD graduate in a relevant field, looking to make a difference in patient lives at the earliest stage of development. You will be one of the first employees working on this groundbreaking science. The ideal candidate will demonstrate an understanding of what it means to be part of an early stage biotech company, the risks involved, and demonstrate commitment to staying with the company long-term.
We are looking for a passionate, independent, and innovative scientist to join our early-stage startup. This scientist will be one that does not simply follow methods/protocols, but is able to develop their own and has a record of solving complex problems with out of the box thinking.
The Research Scientist Intern will be responsible for conducting in vitro and in vivo experiments to help drive preclinical development of our technology. The in vitro work will involve mammalian cell culture (cancer and immune cells), transfection, functional and blockade bioassays, Luminex, ELISA, Western Blot, Flow Cytometry, PBMC cytotoxicity assays, tumor microenvironment modeling, etc.
The in vivo work will involve mouse handling, generation of humanized mouse xenografts with donor PBMC/CD34 cells, tumor implantation, tumor resection, tumor analysis, immunohistochemistry, etc.
The Scientist will also assist in general lab maintenance duties.
Qualifications
- PhD in relevant field (Immunology, Oncology, Molecular Biology, etc) required; exceptions can be made for exceptional candidates with MS degree
- Capacity to independently conduct all aspects of laboratory work, including assay development
- Immune oncology in vivo experience, such as being able to generate humanized mice PBMC or CD34 xenografts, is required
- Strong experience in transfection and culturing of immune and cancer cells is required
- Expertise in Luminex, Western Blot, ELISA, PBMC cytoxicity assays, Functional Bioassays, and rtPCR is required
- Expertise in flow cytometry is required
- Deep understanding of assay development is required
- Experience in modeling of tumor microenvironment preferred
- Expertise in molecular biology and RNA/DNA design principles is highly preferred
- Experience with gene therapy or viral vector systems (i.e. AAV) is preferred
- Experience in 3D cell culture and organoids is a plus
- Ability to analyze and interpret experimental data
- Excellent written and verbal communication skills
- Strong organizational skills and attention to detail
Salary : $16 - $20