What are the responsibilities and job description for the Sr. Scientist, Biology position at Firefly Bio?
About Firefly Bio :
Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. Our mission is to unlock the full potential of bioconjugates and develop medicines with long-lasting benefits for patients. We are establishing an expert team to build state-of-the-art platform capabilities for the invention and development of innovative drug conjugates. Our company culture is built on the values of Focus, Integrity, Respect and Energy. We are looking for passionate individuals committed to making an impact on the future of medicine.
Position Summary :
The Sr. Scientist in Biology will be a key member of the Biology team, leading efforts to understand the mechanistic biology of oncology targets and contributing to program leadership. They will conceive, design, plan, and execute in vitro studies to evaluate novel antibody drug conjugates for applications in oncology and other areas of unmet medical need. The position is lab-facing and on-site. Title and compensation package will be based on experience and relevant skills.
Responsibilities :
- Drive and execute on the design, development, and optimization of in vitro biochemical and cellular assays to evaluate novel payloads, antibodies, and ADCs (antibody drug conjugates) Oversee and contribute to the design and execution of in vitro studies for target validation
- Establish robust in-house capabilities to perform in vitro experiments with high throughput
- Contribute to the understanding of program biology and participate in new target recommendations
- Leverage cell surface target antigen biology to guide therapeutic design and identify appropriate preclinical models
- Collaborate cross-functionally with Protein Sciences and Chemistry teams
- Oversee cell line procurement, evaluation of optimal culture conditions, expansion, storage, and cell line inventory
- Actively participate in department and project team meetings
- Design and manage CRO studies where applicable to support internal efforts
Requirements and Experience :
6 years of industry experience in cellular assays and drug development research
Benefits
Every team member is essential in shaping Firefly Bio’s culture and science and for our success. We offer competitive compensation packages including stock options and the opportunity to be part of ground-breaking research. Firefly Bio is an equal opportunity employer and will consider all applicants for employment. Firefly Bio does not discriminate based on race, sex, color, religion, age, national origin, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits.
