What are the responsibilities and job description for the Associate Director, Radiation Science & Molecular Imaging position at Fusion Pharmaceuticals?

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes, but is not limited to : FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. Fusion has multiple other pipeline programs that will soon be entering into early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radioconjugate manufacturing facility to meet supply demand for our growing pipeline of RCs.

If you think you are the right match for the following opportunity, apply after reading the complete description.

Responsibilities

Review and optimization of nuclear medicine imaging protocols, including review of parameters for QC, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
Set the requirements for the execution of imaging at clinical sites, including providing technical support to study sites.
Design quality control protocols and collaborate with in-house and external resources for imaging review and processing.
Provide training, teaching, and problem-solving solutions to internal and external clinical study teams to meet the needs of the study.
Partner with Radiation Science team in the design quality control protocols and collaborate with in-house and external resources for imaging review and processing.
Collaborate with Radiation Science team on the review and optimization of nuclear medicine imaging protocols, including review of parameters for QC, image acquisition and reconstruction, radiation dose determination, and protocol dose management.
Collaborate with Radiation Science team with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g., SNMMI, NRC, and other country regulatory bodies)
Willingness to travel when needed (10-20%)

Qualifications

The candidate should have a bachelor’s degree in physical or computational sciences or mathematics is required. A graduate degree (M.S. or PhD) would be preferred but not required.

Minimum of 2-5 years of clinical experience / exposure is preferred but not required.

Experience working in clinical trials for 2-5 years is preferred but not required.

Demonstrated technical and analytical problem-solving skills.

Experience with radiopharmaceuticals, Nuclear Medicine, SPECT and PET imaging techniques, reconstruction, and camera quality control procedures required.

Board certification (ABR, ABSNM, CNMT, RTT, CMD) is preferred not required.

Basic understanding of radiation biology and radiation physics are preferred.

Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imaging and dosimetry packages is preferred.

Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS is required and, client / server architectures and image processing is preferred.

Understanding of imaging-related project needs as expressed in a clinical study protocol.

Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g. AAPM, SNMMI, NRC, and other country regulatory bodies)

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

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Associate Director, Radiation Science & Molecular Imaging

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