Scientist I - Upstream Process Development Lead

Summary:

As a Scientist I in Upstream Process Development, you will play a pivotal role in the design, optimization, and scaling of viral vector manufacturing processes, with a focus on upstream processing. You will be responsible for overseeing and developing technology, culture conditions and ultimately platforms for viral vector production, contributing to the advancement of our internal and external client programs.

Key Responsibilities:

· Design and execute experiments to develop, optimize, and scale upstream processes for gene therapy projects.

· Collaborate with cross-functional teams to integrate upstream processes with downstream processes and analytical methods.

· Evaluate and implement innovative technologies and methodologies to enhance process efficiency and productivity.

· Analyze and interpret experimental data, troubleshoot process issues, and make data-driven recommendations for process improvements.

· Document all experiments, results, and procedures in a clear and organized manner to ensure compliance with GDP standards.

· Stay current with industry trends and research to maintain a high level of scientific knowledge and expertise.

· Mentor, manage, and support junior team members, contributing to a collaborative and productive work environment.

· Present development updates to clients and align on delivery of key project milestones.

Qualifications:

· Ph.D. in a relevant scientific discipline (e.g., Bioprocess Engineering, Cell Biology, Biochemistry, or related field) with 0-2 years industry experience, a Masters degree with 2-4 years of industry experience, or a Bachelor’s degree with 3-5 years industry experience.

· Proven experience in developing upstream processes for gene therapies and/or viral vector production (bioreactors, expansion/feeding strategies, and harvest unit operations)

· Ability to scale fermentation/suspension cell culture systems from benchtop to clinically relevant scales.

· Strong understanding of cell and gene therapy and regenerative medicine concepts.

· Excellent analytical and problem-solving skills with a demonstrated ability to work independently and as part of a team.

· Proficient in DOE, data analysis and statistical software (JMP experience desired)

· Knowledge of cGMP, QBD and regulatory requirements is a plus.

· Strong communication skills, both written and verbal.

· Exceptional attention to detail and a commitment to quality in all aspects of work.

What We Offer:

· Competitive salary and benefits package.

· Opportunities for professional growth and career advancement in a dynamic and innovative company.

· A collaborative and inclusive work environment.

· The chance to make a meaningful impact on the future of cell therapy and regenerative medicine.

· If you are a highly motivated scientist with a passion for cell therapy and bioreactor wave technology, we encourage you to apply for this Scientist I position in Upstream Cell Therapy Process Development.

To apply, please submit your resume, cover letter, and any relevant publications to [your application submission method, e.g., email or online portal].

GeneFab is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.