What are the responsibilities and job description for the Senior/Staff Engineer, Application position at Glyphic Biotechnologies?
About Glyphic:
At Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule proteome sequencing platform that will transform life science discovery and usher in a new era of insights into human biology and disease. To date, we have raised >$50M from venture partners and non-dilutive grant funding to achieve our vision of next generation proteome sequencing.
What we are looking for in you:
Glyphic is seeking an experienced applications engineer to translate our cutting-edge single molecule proteome sequencing protocols to automated instrumentation. The ideal candidate will have extensive experience developing complex assays on the Hamilton Star liquid handling platform for DNA & protein biochemistry and/or NGS applications. The engineer will work with a cross-disciplinary team of chemists, biologists, engineers, and bio-informaticians to deploy robust production processes across a range of laboratory automation and custom microfluidic instruments.
Responsibilities:
Compensation Range: $146K - $213K
At Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule proteome sequencing platform that will transform life science discovery and usher in a new era of insights into human biology and disease. To date, we have raised >$50M from venture partners and non-dilutive grant funding to achieve our vision of next generation proteome sequencing.
What we are looking for in you:
Glyphic is seeking an experienced applications engineer to translate our cutting-edge single molecule proteome sequencing protocols to automated instrumentation. The ideal candidate will have extensive experience developing complex assays on the Hamilton Star liquid handling platform for DNA & protein biochemistry and/or NGS applications. The engineer will work with a cross-disciplinary team of chemists, biologists, engineers, and bio-informaticians to deploy robust production processes across a range of laboratory automation and custom microfluidic instruments.
Responsibilities:
- Design, develop, deploy, and rapidly improve automated protein sequencing solutions in a fast-paced startup environment.
- Evaluate new instrumentation fit for purpose and integrate new automated capabilities into existing platform
- Partner with R&D to translate existing benchtop protocols and new protocol concepts across multiple platforms to demonstrate feasibility
- Define standardized liquid handler programming schema for rapid protocol, labware, and liquid class reusability
- Utilize scheduling software to integrate multiple instruments and optimize automated protocols for throughput
- Analyze complex experimental data, generate detailed reports, and provide actionable insights to guide further development.
- Maintain expertise on alternate methods, techniques and best practices used in the field; routinely benchmark process performance
- Thoroughly document the development lifecycle:
- User requirements and instrument selection
- IQ/OQ/PQ
- Operator SOPs and training materials
- Instrument docs and maintenance procedures
- Degree in bioengineering, biology, chemistry, or related field, PhD preferred
- 6 years hands-on industry experience with liquid handlers and lab automation
- Extensive experience developing assays on Hamilton Microlab Star / Venus
- Experience troubleshooting complex instrument/assay issues, performing root cause analysis, and driving corrective actions in a production environment
- Experience quantifying and qualifying your work through IQ/OQ/PQ
- Experience with laboratory information management systems
- Advanced programming and data modeling/analysis skills (Python, C , vendor platforms)
- Experience with protein-based assays, nucleic acids biochemistry, and bioconjugation
- Experience developing and deploying methods in a regulated environment (GxP/CLIA/CAP/ISO)
- Experience with instrument integrations and scheduling software
- Experience developing of a commercial product
- Employee Stock Option Plan
- 100% Health Plan Coverage for Employees & Dependents (Medical, Dental, & Vision)
- Employer Retirement Contributions to 401(k)
- Generous Paid Time Off
- Paid Maternity and Paternity Leave
- Health & Wellbeing Program
- Office Snacks and Beverages
- Regular Team Bonding Activities
Compensation Range: $146K - $213K
Salary : $146,000 - $213,000