What are the responsibilities and job description for the Oligo Platform Biology Senior Scientist/Investigator position at GSK?
Site Name: USA - Massachusetts - Cambridge
Posted Date: Feb 24 2025
The successful candidate will help establish and manage sequencing for GSK”s new oligo platform biology team. Areas of focus are: establishing RNA seq and Amplicon seq capabilities, building a team to support both project screening and exploratory biology efforts and serving as the sequencing expert for the team. Oligo modalities for evaluation include ASO, siRNA, SSO and RNA editing oligos.
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
If you have the following characteristics, it would be a plus:
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or 1 801 567 5155 (outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
Posted Date: Feb 24 2025
The successful candidate will help establish and manage sequencing for GSK”s new oligo platform biology team. Areas of focus are: establishing RNA seq and Amplicon seq capabilities, building a team to support both project screening and exploratory biology efforts and serving as the sequencing expert for the team. Oligo modalities for evaluation include ASO, siRNA, SSO and RNA editing oligos.
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…
- Establish robust and reproducible, high throughput (96/384) RNA seq and amplicon seq assays for the team, including library prep, qc and sequencing
- Manage sequencing efforts for a range of diseases and targets as well as for platform-based development
- Develop efficient workflows and SOPs to build a strong foundation for the team
- Serve as the sequencing representative for Oligo Biology in various meetings/discussions
- Recruit, manage and develop a small team (1-2) to enable successful delivery of project and platform goals
- Independently design, execute and troubleshoot experiments including the analysis and presentation of data across groups
- Continually optimize and validate new biological assays to drive identification and characterization of superior oligonucleotide therapeutics at GSK
- Collaborate and communicate across various teams to build robust workflows, or leverage internal resources to deliver on portfolio endpoints
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
- PhD with 3 years, MS with 6 or BS with 10 years’ experience in molecular or cell biology or related field
- Experience with various NGS assays including RNA sequencing and Amplicon sequencing
- Expertise in RNA biology, assay development and troubleshooting
- Experience with therapeutic oligonucleotides (ASO, siRNA, SSO’s, RNA Editors)
If you have the following characteristics, it would be a plus:
- Master's Degree or PhD
- 1 years of supervisory/management experience
- Experience with high throughput liquid handlers is a plus
- Experience with Nanostring, long-read seq and ddPCR is a plus
- Independent individual with strong initiative
- Excellent written and verbal communication skills, attention to detail, organizational skills, and the ability to collaborate effectively with a team are required
- Sense of urgency, flexibility, independence and accountability
- Ability to communicate both verbally and in writing with all levels both inside and outsider of organization.
- Maintain a high level of integrity while balancing multiple priorities and responsibilities.
- Must be a committed team player prepared to work in and embrace a team-based culture.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or 1 801 567 5155 (outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
