Demo

Senior Manufacturing Technician

HarveStaff
Berkeley, CA Full Time
POSTED ON 1/21/2025
AVAILABLE BEFORE 4/20/2025

Job Summary

We are looking for a dedicated Manufacturing Technician to join our team in the biotechnology industry. The successful candidate will be responsible for assembling and operating cell culture bioreactor systems, including managing gas supply, micro-sparger assembly, and anti-foam emulsion systems. You will also prepare and control continuous cell separation equipment and execute membrane absorption chromatography processes.

Job Description

  • Prepares process equipment (including but not limited to Bioreactors & ancillary equipment,
  • Stainless steel tanks, Pressure Transmitters, Flow Meters, Aggregate traps, Harvest discards, Transfer lines (buffers, cTCF), Hoses, and small parts.
  • Cleans and sterilizes equipment using appropriate CIP (Clean-In-Place), SIP (Steam-In Place) procedures.
  • Performs daily or routine process operations in the cell culture and purification of biotech and biological products (Kovaltry, Kogenate, and Jivi).
  • Inoculates and monitors bioreactors.
  • Processes cTCF material to Continuous Cell Separation (CCS).
  • Operates Chromatography, MAEF, MAVF, and TFF skids.
  • Processes MAEF material using a closed thaw process, step elution chromatography,
  • Membrane Absorber and filter clearance technology, and gradient-controlled SP column separation techniques.
  • Operates 50L, 200L and 1000L collection bag technology to ensure robust collection,
  • mixing and dilution of products.
  • Performs PEGylation of JIVI in process material using TFF technology.
  • Operates automated bagging systems.
  • Blast Freezes product for storage.
  • Dispenses chemicals and formulates solutions.
  • Prepares acids and bases as necessary.
  • Performs aseptic operations.
  • Takes, analyzes and submits samples as required throughout the process.
  • Monitors and controls operation with computer control systems.
  • Completes all routine check sheets.
  • Cleans equipment and maintains clean and orderly production facilities.
  • Performs in-depth troubleshooting and root cause analysis of Kovaltry, Kogenate, and Jivi equipment and process failures.
  • Contributes to continuous improvement opportunities.
  • Performs all operations in compliance with cGMP.
  • Performs other related duties as assigned.

Skills Required

  • Relevant biotech industry experience in some or all of the following is preferred and may be considered in lieu of some or all of the educational requirements above
  • Basic knowledge of protein chemistry and purification systems such as anion, cation, and immunoaffinity chromatography.
  • Education / Training / Certifications

  • Requires completion of two-year college science courses (e.g. biology, chemistry, biochemistry, or microbiology) or a certificate from an accredited biotechnology academy.
  • Additional Requirements

  • Worker Shift Start Time - 08 : 00 PM.
  • Pay Rate / Salary

  • Starting from $25.00 and more based on qualifications.
  • We are an Equal Opportunity Employer. Employment decisions are made without regard to race, color, religion, sex, sexual orientation, age, national origin, disability, protected veteran status, gender identity, or any other factor protected by applicable federal, state, or local laws."

    JOB-10043372

    Salary : $25

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