Research Technician I - Lefkowitz Lab

Primary Work Address: MSRB 1, Suite 301, Research Drive, Durham, NC, 27710 Current HHMI Employees, click here to apply via your Workday account. We are currently looking for a dynamic, driven, and curious Research Technician I within the lab of Dr. Robert Lefkowitz at Duke University in Durham, North Carolina. The lab seeks to understand the molecular mechanisms of a family of cell-surface proteins called G protein-coupled receptors (GPCRs) applying biochemical, medicinal-chemistry, structural, and cellular techniques. GPCRs are the targets of roughly one-third of all prescribed human therapeutics. More information on the work of the lab can be found on their website. We are looking for someone with a strong background in natural sciences who has a passion for continuing to push the boundaries of our understanding. This position will be focused on elucidating the structural basis of G protein-coupled receptor signaling. Thus, the candidate will have a unique opportunity to learn cutting-edge structural biology methods such as X-ray crystallography and cryo-electron microscopy. The ideal candidate will not only be innately curious, but also a consummate team player and interested in being a good lab citizen. Depending on abilities, this person may have the opportunity to eventually run their own project after getting their sea legs within the lab. This is due to the strong collaborative nature of the work and the trust placed in Technicians within the Lefkowitz Lab. Our ideal candidate would be interested in joining the lab for a period of 2-3 years. What we provide: A competitive compensation package, with comprehensive health and welfare benefits. A flexible schedule One on one mentorship relationship What you’ll do: Work efficiently and cooperatively to assist Postdocs, Graduate Students, and other lab members with experiments Perform a variety of laboratory and investigative procedures – including routine experimental techniques such as electrophoresis, centrifugation, Western blot analysis, PCR, molecular cloning, and tissue culture Express and purify proteins by chromatography and perform crystallography screening Collect, verify, record and compile data and information Participate in laboratory meetings and read literature applicable to the research area Help with lab organization, including accurate documentation and recording/maintenance of large data files Assist with other support duties relating to lab operations as required – such as stocking supplies, cleaning glassware, making common reagents, etc. What you bring: Bachelor’s/Master’s degree in Biology, Chemistry or a related field Prior experience working in a research laboratory Experience in protein biochemistry including expression, chromatographic purification, and analysis is a strong plus Understanding of basic molecular biology, biochemistry, and related fields Excellent analytical, communication, problem solving, and organizational skills Ability to work both independently and as a team member while engaged in collaborative studies Able to learn complex tasks with instruction, and to use experience to perform a variety of new techniques Actively seeks opportunities to increase skills and expertise Physical Requirements: Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis. Please Note: This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act. Compensation and Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. HHMI is an Equal Opportunity Employer Compensation and Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. Compensation Range $15.53 (minimum) - $19.41 (midpoint) - $25.24 (maximum) Pay Type: Hourly HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range. HHMI is an Equal Opportunity Employer Howard Hughes Medical Institute (HHMI) is an independent, ever-evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long-term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time. Why HHMI To move science forward we need a diverse collection of talents, expertise, and backgrounds in scientific research and science education, as well as communications, finance, human resources, information technology, investments, law, and operations. At HHMI, we encourage collaborative and results-driven working styles and offer an adaptable environment where employees can do their best work. What makes us strong is the diversity of our perspectives. We work to promote a culture of inclusion in our work environments and across the greater scientific community. To find more information about us and the steps we're taking to make HHMI a more inclusive organization, visit our About Us page. A Note for Job Seekers Your best option for consideration in our career opportunities is to apply directly via our HHMI Careers site. There, you will learn more about HHMI and can find information about our available roles. Contact us at recruitingsupport@hhmi.org if you require an accommodation related to completing the job application. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations.

Salary : $16 - $19