Research Technician - Moura Silva Lab

Primary Work Address: 50 Blossom Street, Boston, MA, 02114 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biomedical research organization and philanthropy, HHMI supports a vibrant community of academic researchers, educators, students, and professionals. Together, we’re unlocking the fundamentals of biology and building an open, inclusive future for science. The lab of Dr. Hernandez Moura Silva at the Ragon Institute of Mass General, MIT, and Harvard has a dedicated focus on the understanding of immune mediated circuits that support the visceral white adipose tissue activity. The white adipose tissue is a fundamental endocrine organ for day-to-day life. It participates in the control of several fundamental systemic homeostatic activities, such as glucose and lipid homeostasis, appetite regulation, hormone production among others. More information about the lab and their work can be found by visiting https://www.immunophysiology.rocks/ This position is expected to begin after September 1st, 2023 in concurrence with Dr. Moura Silva’s upcoming appointment as a Freeman Hrabowski Scholar. About the Research Technician role: As the Research Technician, you will join a dynamic and exciting research team at the forefront of macrophage cellular immunology and perform experiments to characterize how the activity of these cells impacts the functionality of the white adipose tissue and systemic metabolism. Additionally, the position also offers opportunities to be involved in projects to develop new tools to manipulate macrophages in vivo. One long-term objective of the lab is to develop new strategies to combat metabolic diseases such as type 2 diabetes. This would be an ideal position for a hardworking, enthusiastic, self-motivated person who is looking for a robust 2-year career experience that will give them a strong foundation in science and research as well as guided mentorship to help successfully transition into graduate school or medical school. What we provide: A competitive compensation package with comprehensive health and welfare benefits The opportunity to learn new scientific approaches through access to cutting-edge facilities and expand your knowledge and skills Joining the vibrant Ragon Institute and larger MGH/MIT/Harvard research community Access to HHMI’s Udemy on-demand training courses and interactive skill-building seminars taught by members of our learning and organization development team Working with and being directly mentored by an investigator that has a deep commitment to diversity, equity, and inclusion What you’ll do: Under the general direction of senior members of the lab team, independently carry out daily activities and divide efforts between independent projects, animal husbandry, and lab organization. Actively participate in scientific activities such as seminars, lab meetings, and journal club in addition to experimental obligations. Prepare basic solutions and performs base-level procedures as assigned (i.e. – pipetting, cell and tissue culture, etc.). Support animal experiments (with mice) through husbandry, genotyping, euthanasia, and dissection. Perform assays using standard techniques (antibody staining, flow cytometry, microscopy, DNA/RNA extraction and analysis, standard and quantitative PCR, ELISA, cloning). Analyze experimental results and troubleshoot methods to improve research protocols. Maintain organized records, back-ups and documentation of all experimental procedures. Report results to investigator or other senior lab team member as required in verbal and written form. Cell/tissue processing, culture and maintenance. Independently performs routine and non-routine experiments that are moderate to complex. Assist Lab Manager in cleaning and maintaining laboratory equipment and instrumentation (e.g., biosafety cabinets, incubators, and other equipment); monitors levels of and packages biological waste for disposal. Other tasks as required or assigned. What you bring: A bachelor's degree in biology or a closely related subject area is required. Previous hands-on experience working in an academic research laboratory environment is required. Proficiency in basic lab techniques and principles of molecular biology such as DNA/RNA isolation, cloning, standard and real time PCR is strongly preferred. Exceptional organizational skills, attention to detail, and documentation skills. Exceptional interpersonal skills and ability to work well with not only lab members but also with facilities and administrative personnel. Exceptional verbal and written communication skills. Willingness to make a commitment to work in the lab for 2 years. A high degree of motivation, proactiveness, and initiative. Ability to present data at internal lab meetings and conferences. Ability to work both independently and as a member of the team. Demonstrated commitment to honesty, integrity, and reliability. Positive attitude with an eagerness to learn and grow. Comfort and willingness to work with laboratory mice on a day-to-day basis is required. Previous experience working with mice is preferred, but not required. Proficiency and/or demonstrated ability to learn computer software platforms. Please include a list of three (3) professional references with contact information as part of your application. Physical Requirements Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials. Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis. Please Note: This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act. Compensation Range: Research Technician I – $17.08/hour ($35,530/year) minimum - $21.35/hour ($44,400/year) midpoint - $27.76/hour ($57,750/year) maximum Pay Type: Hourly HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range. Compensation and Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. HHMI is an Equal Opportunity Employer Howard Hughes Medical Institute (HHMI) is an independent, ever-evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long-term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time. Why HHMI To move science forward we need a diverse collection of talents, expertise, and backgrounds in scientific research and science education, as well as communications, finance, human resources, information technology, investments, law, and operations. At HHMI, we encourage collaborative and results-driven working styles and offer an adaptable environment where employees can do their best work. What makes us strong is the diversity of our perspectives. We work to promote a culture of inclusion in our work environments and across the greater scientific community. To find more information about us and the steps we're taking to make HHMI a more inclusive organization, visit our About Us page. A Note for Job Seekers Your best option for consideration in our career opportunities is to apply directly via our HHMI Careers site. There, you will learn more about HHMI and can find information about our available roles. Contact us at recruitingsupport@hhmi.org if you require an accommodation related to completing the job application. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations.

Salary : $17 - $35,530