What are the responsibilities and job description for the Medical Director position at Immunome, Inc.?
Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.) Our most advanced pipeline programs are varegacestat (formerly AL102), a gamma secretase inhibitor which is currently in a Phase 3 trial for treatment of desmoid tumors, IM-1021, a ROR1 ADC with an active IND, and IM-3050, a FAP-targeted radioligand, which is the subject of an IND expected to be submitted in the first quarter of 2025. Our pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors.
Position Overview
We are seeking a highly motivated and experienced Medical Director to lead and oversee the medical and clinical development strategy for Immunome’s early stage therapeutic programs. The ideal candidate will have a deep understanding of oncology with expertise in translational science and clinical development. The Medical Director will play a crucial role in designing and executing clinical trials, engaging with key stakeholders, and ensuring regulatory compliance.
Responsibilities
$272,356 - $318,201 USD
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.) Our most advanced pipeline programs are varegacestat (formerly AL102), a gamma secretase inhibitor which is currently in a Phase 3 trial for treatment of desmoid tumors, IM-1021, a ROR1 ADC with an active IND, and IM-3050, a FAP-targeted radioligand, which is the subject of an IND expected to be submitted in the first quarter of 2025. Our pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors.
Position Overview
We are seeking a highly motivated and experienced Medical Director to lead and oversee the medical and clinical development strategy for Immunome’s early stage therapeutic programs. The ideal candidate will have a deep understanding of oncology with expertise in translational science and clinical development. The Medical Director will play a crucial role in designing and executing clinical trials, engaging with key stakeholders, and ensuring regulatory compliance.
Responsibilities
- Lead and execute the clinical development plan for novel early stage therapies in the pipeline.
- Provide strategic clinical leadership and hold responsibility for all clinical deliverables.
- Develop protocols consistent with Clinical Development Plans (CDP), clinical components of regulatory documents, and publications.
- Oversee protocol development, study design, and data interpretation to drive clinical decision-making.
- Serve as the primary Medical Monitor for assigned programs, including overseeing internal and external teams and providing medical guidance to CRO partners and clinical sites.
- Collaborate with translational sciences to ensure key pharmacodynamic and biomarker endpoints are incorporated into the study design and executed.
- Manage budget and resources in coordination with the Chief Medical Officer (CMO).
- Engage with external stakeholders (e.g., regulatory authorities, key opinion leaders, advisory boards, patient advocacy groups) and internal teams (e.g., Research, Translational Sciences, Clinical Operations) to ensure alignment with corporate strategy.
- Provide medical oversight for safety evaluations, risk assessments, and regulatory submissions.
- Support business development efforts by assessing new opportunities and partnerships from a clinical perspective.
- Stay abreast of the latest advancements in immunology, oncology, and infectious diseases to guide strategic decision-making.
- Represent Immunome at scientific conferences, advisory boards, and investor meetings as needed.
- M.D., D.O., or equivalent with clinical research experience in oncology, hematology, immunology, or related fields.
- Board certification in Medical Oncology, Hematology, or a related field is preferred.
- Minimum of 3 years of experience in clinical development, preferably within the biotechnology or pharmaceutical industry.
- Proven track record of designing and executing clinical trials, primarily early-phase. Experience with radioligand therapies is a plus.
- Familiarity with FDA and EMA regulations, processes, and guidelines, with experience in leading regulatory interactions.
- Experience progressing therapeutic programs from IND-enabling studies into the clinic.
- Excellent communication and leadership skills, with the ability to collaborate effectively across diverse teams.
- Experience engaging with key opinion leaders, academic institutions, and industry partners.
- Ability to work in a fast-paced, dynamic environment and contribute to strategic decision-making.
$272,356 - $318,201 USD
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Salary : $272,356 - $318,201
