What are the responsibilities and job description for the Senior Director, Pathology position at Immunome, Inc.?
Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.) Our most advanced pipeline programs are varegacestat (formerly AL102), a gamma secretase inhibitor which is currently in a Phase 3 trial for treatment of desmoid tumors, IM-1021, a ROR1 ADC with an active IND, and IM-3050, a FAP-targeted radioligand, which is the subject of an IND expected to be submitted in the first quarter of 2025. Our pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors.
Position Overview
The Senior Director, Pathology will develop and implement comprehensive plans to support optimal nonclinical packages for candidate drugs in all stages of development from developing liability assessments and advising on early screening assays to submission of NDA / BLAs. In this role, they will lead the design, development, and implementation of toxicology plans and pathology solutions for multiple oncology programs, enabling the optimal clinical development of candidate drugs. This role reports to the Executive Director, Toxicology.
Responsibilities
- Author relevant sections of clinical protocols and regulatory submissions (such as IBs, CTDs, INDs, BLAs).
- Proactively develops plans to provide stage specific data for all assets from late-stage research through regulatory submission for drug approval. Executes on the plans to provide high quality data to support internal decision making and regulatory submissions.
- Provide pathology support for exploratory and development (e.g. GLP) pathology endpoints on internal and external in vivo studies across the pipeline.
- Actively partners with other functions and departments to ensure that programs are progressed seamlessly through the development process.
- Act as a pathology and pathogenesis subject matter expert in Translational Sciences, providing key strategy and analysis cross-functionally for discovery, target expression and validation, animal model, and biomarker efforts across the organization.
- Participates in assessment of in license assets to provide a recommendation to senior management.
- Represents the function at internal and external meetings, providing clear assessment of data to communicate the potential and value of pipeline assets.
- Actively participates in functional meetings.
Qualifications
Knowledge and Skills
Washington State Pay Range
284,000-$320,000 USD
E / E / O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Salary : $284,000 - $320,000
