Research Scientist II, Applied Science in Therapeutic Oligonucleotides

Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications. Our work is complex and cutting-edge, and our team members are curious, creative thinkers who understand that good data drives smart decisions. At IDT, we realize that although science may be uniform, people are unique. We promote a culture where engaged people are motivated and have opportunities to achieve their full potential, as part of one global team.

IDT is one of 10 Life Sciences companies of Danaher. Together, we accelerate the discovery, development and delivery of solutions that safeguard and improve human health.

This position is part of the Applied Sciences for Therapeutic Oligonucleotides team in our Gene Writing and Editing Business Unit located in Coralville, Iowa and will be on-site. At IDT, we are one global team. We celebrate our differences, engage in healthy debate, and are inclusive. Together, we accomplish great things!

In this role, you will have the opportunity to:

• Function as a scientist at the bench, under minimal supervision, reporting to a team or project lead and executing projects as part of IDT’s new Genomics Medicine Service offerings related to: off-target safety assessment for CRISPR-based editing systems, CRISPR guide RNA sequencing, and additional, custom projects associated with IDT’s Therapeutic Oligonucleotides business
• Provide teamwide scientific support on all aspects of therapeutic oligonucleotides projects inclusive of lab work, project tracking and organization, data collection, data analysis, report generation, and data presentation
• Plan and keep detailed experimental records in facilitating technology transfer of methods from R&D to the Gen Meds Services team; gain expertise in technologies to support further feasibility, development and validation of assays as well as propose ideas for broader use and application
• Lend subject matter expertise to customer-specific oligo assessment of quality, performance, safety, etc. in cell-based, biochemical or analytical assays; assist in the definition of technical and experimental work plans related to on-going efforts to advance customer projects while supporting customer progress towards cGMP oligonucleotide synthesis
  
  

The essential requirements of the job include:

• Bachelor’s degree (in Biology, Genetics, Chemistry or a related life sciences field) with three or more years relevant lab experience OR a Master’s degree (in Biology, Genetics, Chemistry or a related life sciences field) with one or more years relevant lab experience
• Demonstrated experience and technical background in CRISPR and Gene Editing rooted in research, development, or applications
• Demonstrated expertise in basic techniques in biochemistry, cell biology, genomics, or related field
• Demonstrated background competency in cell culture techniques, delivery of genome editing components to various cell types, and/or management of good laboratory practices in a tissue culture lab
• Demonstrated abilities in project organization, critical thinking, and team work applied to experimental planning, data analysis and data presentations
  
  

Travel, Motor Vehicle Record & Physical/Environment Requirements:

• Ability to travel domestically and internationally less than 10%
  
  

It would be a plus if you also possess previous experience in:

• Delivering results in a regulated space (GLP, ICH, cGMP, etc.)
• Demonstrated experience in next-generation sequencing technology development and/or application
• Bioinformatics related to assessment of genome editing or working with bioinformatics experts towards NGS-based assessment of genome editing events
• Operating under design control and design assurance in product development
• Custom genomics product development, verification or validation
  
  

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

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We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation.