What are the responsibilities and job description for the Bioanalytical Scientist position at Integrated Resources, Inc ( IRI )?
We are developing a pipeline of gene therapies to slow or stop the underlying disease process for patients with genetic disorders. We are leveraging recent breakthroughs in human genetics that point to potential disease-modifying targets for diseases. Our programs utilize a precision medicine approach targeting patient populations with urgent unmet needs, where there are currently no available therapies that modify the progressive course of their disorders.
Meet Your Future Team:
The Analytical Development team is a tight-knit group of energetic, smart, fun, and motivated individuals. We work closely on Gene Therapy’s Adeno-Associated Virus (AAV)-based gene therapy programs to progress our mission of curing disease. We are a tight-knit group within team, responsible for developing and running robust and innovative analytical methods to support internal and external manufacturing processes, while also staying on the cutting-edge of industry standards.
While much of the day-to-day operations require wet-lab work, our team focuses on not only building everyone’s technical expertise but also fostering an environment for career growth as scientists in the biopharmaceutical industry. As analytical development relates to quality, process development, preclinical and clinical R&D, manufacturing, and regulatory functions, there is opportunity for exposure to the whole Product of biopharmaceutical industry processes. We are seeking a motivated research associate who can take on ownership of established molecular biology assays as well as contribute to the development of new cutting-edge assays for testing AAVs.
Responsibilities:
- Contribute to all aspects of analytical assay development, from design to qualification, for our AAV-based drugs.
- Contribute to the development and qualification of new molecular bioassays for AAVs including titer, genomic integrity, and next-generation sequencing assays.
- Perform testing in support of AAV programs using techniques such as ddPCR, agarose gel electrophoresis, chromatography, and NGS.
- Analyze, document, and report data.
- Write technical reports and SOPs.
- Communicate data within the group as well as across functions.
Qualifications:
- BS or MS with 2 years of lab experience with molecular biology techniques.
- A skill set which may include qPCR/ddPCR, next-generation sequencing, spectrophotometry, gel/capillary electrophoresis, SDS-PAGE/Western blot, or others.
- Experience with separation-based analytical techniques such as HPLC and chromatography is desirable.
- Understanding of analytical method lifecycle of development, qualification, validation, and documentation is a plus.
- Prior experience with AAVs is a plus.
- Strong organizational and problem-solving skills and attention to detail.
- A passion for learning, understanding, and advancing science.
- Motivation to learn new skills both inside and outside the lab.
- Ability to work independently and in a dynamic team environment.
- Excellent verbal and written communication skills.
