Chemist

Title: Biochemist/ Research Associate

Location: Chesterfield – MO

Duration: 10 months

Job Description:

• The incumbent will participate in the formulation and process development of biotherapeutics.
• This position will be responsible for performing analytical characterization of candidate molecules by using various biophysical, biochemical and particulates characterization techniques.
• This is a laboratory-based position performing formulation and process development activities specifically for biotherapeutic products from pre-clinical and Ph I clinical trials through late stage, license application and commercialization.
• Furthermore, this position will assist in data compilation, data presentations, and report writing.
• Support the development of parenteral formulations for biotherapeutic modalities such as monoclonal antibodies, antibody drug conjugates, proteins, and vaccines.
• Perform rapid, comprehensive characterization of candidate molecules to determine the stability profile.
• This will be achieved by applying various biophysical, biochemical, particulates characterization techniques such as HPLC (SE-HPLC, IEX, HIC, RP-HPLC), Capillary Gel electrophoresis (CGE), imaged Capillary Electrophoresis (iCE), Spectroscopy techniques, light obscuration, microflow imaging and additional characterization techniques.
• The incumbent must be able to interact effectively with a multidisciplinary team of scientists for formulation optimization and overall candidate progression.
• This position will be responsible for preparing data summary presentations, compiling data and using lab-based systems for data collection such as empower and electronic laboratory notebooks.

Technical Skills:

• Familiarity with biologics such as proteins, enzymes, monoclonal antibodies, vaccines, or antibody drug conjugates and how to characterize them with analytical techniques

Desirable:

• Familiarity with HPLC, Capillary electrophoresis, and other analytical techniques.
• Strong computer skills and experience with lab-based computer systems.
• Ability to collect and analyze data sets.

Hard Skills:

• Material weighing
• Lab scale balance use
• Buffer preparation
• Pipetting

What is the minimum education experience required:

• Bachelor’s of Science (or Arts) in Chemistry, Biology, Chemical Biology, Biochemistry, Biomedical Engineering, Chemical Eng, Microbiology Basic Lab techniques learned in classroom lab and/or research/academic/industry laboratory.
• Minimum 2 years in academic lab and 0-3 yrs in industrial lab.