Demo

Translational Research Scientist - II

Intelliswift Software Inc
South San Francisco, CA Full Time
POSTED ON 2/21/2025
AVAILABLE BEFORE 4/19/2025
Qualifications:
Required Experience and Skills:
• B.S with minimum 5 years'; Masters with 3 years'; PHD with 1-2 years' of relevant work experience in industry or academia
• Experience with immunohistochemistry and multiplexed immunofluorescence assay development
• Experience using digital image analysis software and spatial imaging platforms such as HALO, Visiopharm, QuPath, digital slide scanning, multiplex spectral imaging, Akoya Polaris, Phenocycler/Fusion.
• Strong organizational abilities and communication skills

Preferred Experience and Skills:
• High level of comfort with histology/microanatomy strongly preferred
• Background in oncology and/or immunology
• Programming skills with application in imaging (e.g. Python, MATLAB) data
• Experience with version control environments, such as Git
• Experience with high-performance Linux cluster and cloud computing
• Familiarity with client--servers and cloud computing infrastructure
The Successful Candidate will:
• Perform validation and quality check of the analysis readout on multiplexed immunofluorescence images
• Perform image preprocessing tasks according to established SOPs, including metadata extraction, output quality control, and secure data transfer to cloud storage.
• Assist in evaluating and implementing new algorithms to enhance the image analysis pipeline, such as cell segmentation improvements, tissue classification, and cell phenotyping.
• Assist with the transfer of data and image-related information for analysis, facilitating smooth collaboration between teams.
• Coordinating with IT to
o Gather and document feedback from users on image analysis workflows and tools.
o Address user pain points, define requirements, and improve tool functionality.
o Lead user experience testing, working with IT to implement improvements and optimize tools for production use
o Maintain and update image analysis computers to ensure they remain optimized for routine tasks
• Define and document requirements for new tools and ensure their successful deployment.
• Provide administrative support for multiplex IHC related work, including reagent ordering, capital equipment purchasing, document and maintain SOPs for image processing and analysis workflows.
• Interact smoothly with scientists, computer scientists, and informatics/IT staff, both internally and externally

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