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Research Associate, Antisense Drug Discovery

Ionis
Carlsbad, CA Full Time
POSTED ON 1/22/2025
AVAILABLE BEFORE 4/13/2025

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We are pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With five currently marketed medicines for serious diseases and an expansive late-stage pipeline, we continue to build upon our groundbreaking innovations in science and technology to provide greater value to patients; and we are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know our success is a direct result of the exceptional talent and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money, and energy into making our onsite and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We are building on our rich history, and believe our greatest achievements are ahead of us. We invite you to apply and join us if you're passionate about the opportunity to have meaningful impact on patients in need, our employees, and our organization. Experience and contribute to our unique culture while you develop and expand your career!

RESEARCH ASSOCIATE, ANTISENSE DRUG DISCOVERY

RESPONSIBILITIES :

  • We are seeking a highly motivated and talented individual to join our drug discovery research group as a Research Associate. The selected candidate will work with a multi-disciplinary team of energetic researchers. The successful candidate will be an innovative thinker with the ability to work independently to conceptualize, design and meticulously carry out in vitro and in vivo assays. The position will involve research, development, optimization and troubleshooting of methods to characterize CRISPR gene editing systems, antisense oligonucleotides and siRNAs in cells and animals.

Specific work includes :

  • Conceive, plan, and execute basic scientific experiments to further characterize the mechanism(s) of target modulation.
  • Apply molecular and cell-based assays including but not limited to RNA purification, transfection, gene expression analysis (RT-qPCR & DGE), and fluorescence immunocytochemistry.
  • REQUIREMENTS :

  • B.S. / M.S. degree in Biology or related fields and a minimum of 2 years' experience
  • Strong laboratory skills in standard assays such as RNA and protein isolation, qRT-PCR, ELISA, Western Blotting
  • Proficiency in rodent handling, dosing and necropsy strongly preferred
  • Excellent written and verbal communication skills
  • An ability to be productive and successful in a very demanding and intense work environment
  • Please visit our website, http : / / www.ionis.com for more information about Ionis and to apply for this position; reference requisition #IONIS003517

    Ionis offers an excellent benefits package! Follow this link for more details : Ionis Benefits

    Full Benefits Link : https : / / www.ionis.com / careers / working-at-ionis / # : ~ : text=our employee spotlight-,Benefits,-Employees are rewarded

    The pay scale for this position is $57,635 to $87,766

    NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

    Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

    LI-Onsite

    Salary : $57,635 - $87,766

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