Immunology Scientist

Key Responsibilities

· Design, generate, and characterize CAR T or other constructs for genetically modified T cells.

· Implement existing strategies for highly multiplexed cloning, using either pooled cloning or arrayed cloning approaches

· Implement existing strategies for highly multiplexed cloning, using either pooled cloning or arrayed cloning approaches

· Independently design and lead pre-clinical in vivo studies, including downstream analysis.

· Collect, analyze, and present scientific data in the form of presentations and reports to research and management teams, with proposed next steps.

· Provide conceptual input on experimental design and supervise junior team members.

· Coordinate research efforts with other scientific teams in highly cross-functional projects.

Qualifications / skills

· We are seeking a highly motivated, creative scientist who thrives in a fast-paced and collaborative environment

· The ideal candidate will have extensive expertise in immunology, including a deep understanding of either regulatory T cells (Tregs) or the design of engineered T cell therapies (e.g. CAR-Treg, CAR-T, TCR-T, or others)

· PhD in Immunology, Cancer Biology or a related field with a minimum of 3 years of industry or academic experience working in immunology and in vivo oncology or pharmacology.

· Understanding of the current state of CAR-T cell therapy and challenges within the field. Knowledge of various animal models to analyze the efficacy and safety of CAR-T cell therapy.

· Exceptional laboratory and analytical skills, with demonstrated proficiency in the development and execution of experiments related to CAR-T cells biology.

· A record of publication in immunology, gene therapy, or molecular biology along with good writing and presentation skills are required.

· Work in a team and matrix environment as well as contribute individually to meet project timelines and deliverables.

Valued Complementary Skills

• Hands on experience with human PBMC samples

• Processing and analyzing mouse tissues using various techniques

• Phenotyping and functional analysis of CAR T cells in in vitro and in vivo experiments

• Data analysis

Job Type: Full-time

Pay: $80,000.00 - $95,000.00 per year

Benefits:

• 401(k)
• Dental insurance
• Health insurance
• Life insurance
• Paid time off
• Vision insurance

Schedule:

• Monday to Friday

Experience:

• CAR- T cell therapy: 2 years (Required)
• Immunology: 3 years (Required)
• cloning, qPCR, dPCR: 2 years (Preferred)
• Working with various mammalian cell lineS: 3 years (Required)
• multicolor flow cytometry, ELISpot, Luminex: 2 years (Preferred)

Work Location: In person

Salary : $80,000 - $95,000