What are the responsibilities and job description for the Research Scientist (siRNA) position at JMD Technologies Inc.?
Title: Research Scientist II
Contract Length: 6 months; on-site position
Location: Lexington, MA
Job Summary:
The Research Scientist is a lab-based role with hands on formulation, biophysical and analytical characterization expertise of oligonucleotides for injectable delivery.
Responsibilities:
- Identifies gaps in technological capabilities provides recommendations to guide the research agenda
- Manage multiple external collaborations for deliverables
- Optimize long-term storage and stability conditions of RNAi conjugates and oligonucleotide formulations in general
- Develop robust analytical methods and assays for QC and developability assessments
Requirements:
- 3 years of relevant experience with a PHD (LEVEL II) or 3 years of relevant experience with a Masters (LEVEL I)
- Subject matter expertise in Pharmaceutical Sciences, oligonucleotide/peptide/antibody characterization, or related scientific disciplines
- In-depth and hands-on experience in a range of synthesis, characterization, and purification techniques, including but not limited to NMR, HPLC (analytical and preparative), Mass Spectrometry, IR, silica gel and reverse phase chromatography, TLC, recrystallization etc.
- Acting as formulation subject matter expert for nucleic acid therapeutics.
- Ability to establish screening assays for oligonucleotides in early discovery.
- Experience with analytical method development for solubility, viscosity, degradation and rheological assessment for complex oligonucleotides
