What are the responsibilities and job description for the Research Associate/Senior Research Associate, Mass Spectrometry position at Jnana Therapeutics?
About Us Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases and immune-mediated diseases. Jnana's lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, and a highly experienced management team. For more information, please visit www.jnanatx.com and follow us on Twitter / X and LinkedIn.
At Jnana, you'll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging-making Jnana a great place to work!
About the Opportunity As a Research Associate in our Chemical Biology group, you will support a range of mass spectrometry-based activities by developing and running bioanalytical methods and assays for multiple programs at various stages.
The ideal candidate is enthusiastic, creative, and motivated by a career in analytical drug discovery. You should have a strong foundation in mass spectrometry and its applications in a drug discovery setting. Prior experience in drug discovery and bioanalysis is preferred, but training will be provided for candidates with strong potential. Level can be flexible based on experience.
Responsibilities
- Prepare samples for general bioanalytical and ADME assessments for mass spectrometry-based analysis.
- Develop and validate analytical methods to quantify small molecules and metabolites from various biological matrices.
- Assist with routine maintenance and upkeep on mass spectrometers and liquid chromatography systems to ensure they are operating at peak performance.
- Efficiently generate, analyze, and present data reports to project teams, as well as upload to the internal database.
- Work closely with project teams in the design and execution of studies supporting discovery programs, prioritizing work for execution against timelines.
- Commitment to ongoing professional growth and a passion for driving innovation.
- Opportunities to expand expertise in mass spectrometry-based proteomics assays.
Preferred Qualifications & Experience