Principal Scientist, Computer-Aided Drug Design (CADD) - La Jolla, California

Johnson & Johnson Innovative Medicine (JJIM) is recruiting for a Principal Scientist, Computer-Aided Drug Design (CADD, Computational Chemistry) , to join our In Silico Drug Discovery team located in San Diego, California (La Jolla area). At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https : / / www.jnj.com / . For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges. We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential. At Johnson & Johnson, we all belong. The In Silico Discovery Unit is a computational discovery team embedded in the Therapeutics Discovery organization, a modality agnostic discovery engine within JJIM responsible for driving all aspects of computational drug discovery across J&J's Therapeutic Areas. The In Silico Discovery (ISD) group is seeking excellent scientists to bring their expertise to exciting and novel areas of computational drug design. Key Responsibilities Include :

• Design therapeutic molecules and calculate their properties using state-of-the-art methodologies integrating chemical, biological and structural data, cheminformatics, and artificial intelligence / machine learning techniques
• Serve as a scientific expert in multi-disciplinary discovery project teams that include synthetic chemists, structural biologists, and other discovery scientists, by providing key expertise in the use and interpretation of data related to drug targets and their ligands
• Collaborate within Janssen and with external academic and industrial partners to develop new computational technologies to address key questions in drug discovery
• Publish results in peer reviewed journals and present at scientific meetings
• Mentor junior scientists, fostering their development as expert computational drug hunters
• A PhD in computational chemistry or a related field, with at least 2 years of experience applying computational modeling in a pharmaceutical industry drug design setting is required
• Familiarity with at least one standard computational drug discovery package (examples may include, Maestro / Schrodinger, MOE / Chemical Computing Group, and / or OpenEye tools) is required
• Experience with one or more of : working in a cross-functional environment, mentoring scientists, influencing decisions and resolving conflicts is strongly preferred
• Experience with multiple therapeutic modalities (e.g. small molecules, biologics, peptides, targeted protein degraders) is preferred
• Experience scripting computational workflows in Pipeline Pilot, Knime, Python or Jupyter notebooks is preferred
• Excellent written and verbal communication skills, and a strong publication record is required
• This position is located in La Jolla, CA and requires up to 10% travel domestically and internationally Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. The anticipated base pay range for this position is $115,000 to $197,800. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar / performance year. Bonuses are awarded at the Company's discretion on an individual basis.
• Please use the following language :
• Employees and / or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs : medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company's long-term incentive program.
• Employees are eligible for the following time off benefits :
• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. https : / / www.careers.jnj.com / employee-benefits The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. #LI-SLOPEZ11 #LI-Hybrid #JNJIMRND-DS #JNJDataScience

Salary : $115,000 - $197,800