Senior Director, Early Development Clinical Leader Ophthalmology

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Clinical Development & Research – MD

Job Category

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America, La Jolla, California, United States (inactive), Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America

Job Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/. 

Position Summary

The incumbent will serve as a Clinical Leader in Ophthalmology, Neuroscience, building the Translational Medicine and Early Development Plan and leading the clinical development strategy for early-stage compound(s), in collaboration with Ophthalmology Discovery, Biomarkers, Clinical Development, and other functional partners. This position is accountable for the medical oversight, conduct, and analysis of the appropriate first in human (FIH), proof of pharmacology (POP), proof of mechanism (POM), and proof of concept (POC) studies for NME early development programs and mechanistic trials and clinical pharmacology studies supporting all phases of development for the ophthalmology portfolio.

Essential Functions

• Leading the early development clinical team in the timely completion, content, and quality of key development deliverables including protocols, reports and submissions to health agencies
• Close collaboration with discovery on target identification, biomarker strategies, and NME criteria
• Overseeing active medical and scientific contribution to matrixed cross-functional Early Compound Development Teams and Clinical Teams
• Formulation and implementation of early Clinical Development Plans, including trial design and endpoints
• Working with functional partner leadership (e.g., Global Clinical Operations (GCO), Regulatory, Global Medical Safety) to achieve common goals
• Presenting and/or responding to questions at meetings with Health Authorities, including FDA advisory committee meetings and/or CHMP presentations
• Participating in formulating our strategy as a key leader in the Ophthalmology Disease Area Stronghold Leadership Team
• Providing key input into due diligence activities for Business Development opportunities
• Collaborating across disease areas and therapeutic areas to optimize the reach of Johnson & Johnson’s differentiated scientific expertise and capabilities
• Participating in cross-departmental or cross-functional projects with broad Johnson & Johnson impact
• Building and maintaining relationships with key opinion leaders
• Provides key input into diligence activities
  
  

This is not an exhaustive, comprehensive listing of job functions. May perform other duties as assigned.

Education And Experience

• MD (or equivalent) is required. Board certification in Ophthalmology is preferred
• Detailed and thorough understanding of retinal disorders, including inherited retinal diseases, retinal vascular diseases and degenerative diseases of the macula is required.
• Additional education: Significant academic or pre-clinical research or related experience is especially desirable. Expertise in clinical drug development including demonstrated ability to develop clinical development plans meeting the highest standards is required. Ability to interface effectively with discovery, preclinical, and late clinical development is required. Energy and enthusiasm are essential. Experience working in a Matrix environment is required.
• Excellent oral and written communication and presentation skills are required. The ability to work with cross-functional teams in a matrix environment is required.
• Up to 20% annual travel (domestic and international) may be required.
  
  

Required Technical Knowledge And Skills

• Fluent in written and spoken English
• Working knowledge of the use of Microsoft suite of software products including Excel and Word
• Experience and knowledge of Good Clinical Practices and regulatory requirements for the conduct of clinical trials and for the appropriate contributions to regulatory filings
• Exceptional analytical and critical thinking skills, with the ability to translate complex data (financial/operational) into actionable insights for strategic decision making.
• Exceptional problem-solving skills with the capacity to anticipate risks, to develop creative solutions and to meet objectives.
• Demonstrated ability to develop deep insights (e.g., big picture thinking) based on data analysis and interpretation.
• Results oriented, able to think creatively, critically, and proactively, to drive innovative solutions.
• Breath of experience in leading people of varying levels via coaching and open conversations to reach their full potential, while also providing support and guidance during periods of poor performance.
  
  

Special Training Or Certification

• Board certification in Ophthalmology is preferred
  
  

The anticipated base pay range for this position is $226,000 to $391,000 USD.

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

Employees may be eligible to participate in Company employee benefit programs such as health insurance, savings plan, pension plan, disability plan, long term incentives, vacation pay, sick time, holiday pay, and work, personal and family time off in accordance with the terms of the applicable plans. Additional information can be found through the link below. For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

At Johnson & Johnson, we’re on a mission to change the trajectory of health for humanity. That starts by creating the world’s healthiest workforce. Through cutting-edge programs and policies, we empower the physical, mental, emotional, and financial health of our employees and the ones they love. As such, depending on location and subject to local legislation, candidates offered employment may be required to show proof of COVID-19 vaccination or, in certain countries, secure an approved accommodation prior to the commencement of employment to support the well-being of our employees, their families and the communities in which we live and work. If you are invited to interview for the position, your recruiter will advise on the vaccine requirement status in your geographic location.

Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.

For more information on how we support the whole health of our employees throughout their wellness, career, and life journey, please visit www.careers.jnj.com.