Demo

Principal architect

Karius
Redwood, CA Full Time
POSTED ON 2/19/2025
AVAILABLE BEFORE 5/16/2025

Redwood City, CA (Hybrid)

Software Engineering – Engineering

Full-time / Hybrid

About Karius

Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body. By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to the microbial landscape to accelerate biomarker discovery and clinical trials, discover novel microbes, to ultimately reduce patient suffering worldwide.

Position Summary

Research, development, and operation of Karius’s novel technologies heavily depend on the underlying computing and data infrastructure, software system architecture, and various research and engineering tools (aka, Karius R&D / Ops platform or simply “Platform”). In this critical engineering role, you will collaborate closely with the engineering and science leadership to set the strategic direction for the technology behind this Platform. Then, develop and drive a technology roadmap to develop and operate an extensible, reliable, secure, and scalable Platform.

Reports To : Vice President, Engineering

Location : Redwood City, CA or Hybrid

Primary Responsibilities :

  • Leading architectural projects from concept to completion, ensuring timely delivery and adherence to budget and quality / regulatory requirements.
  • Developing architectural blueprints, frameworks, and guidelines for Platform development and operation.
  • Ensuring the architecture meets technical and business requirements including security, performance, interoperability, and scalability.
  • Staying current with industry trends and emerging technologies to ensure the Platform leverages the best technologies that fit the needs.
  • Articulating and presenting complex ideas clearly and effectively to technical and business audiences.
  • Developing, documenting, and organizing artifacts such as strategy, technical proposals and designs, and risk assessments.
  • Ensuring Karius’s R&D and engineering staff have the proper infrastructure, tools, and processes to be productive.
  • Ensuring the Karius Platform is cloud vendor agnostic, can be provisioned globally using a blueprint as code, and meets regional privacy and security rules and regulations.
  • Enable the Platform to be provisioned for non-Karius laboratories, enabling them to operate Karius products.

Position Requirements :

  • B.S. or M.S. in Computer Science, Electrical Engineering, Physics, Statistics, Biomedical Engineering, Genetics, or a related engineering or science field. Ph.D. in these fields is a big plus.
  • 15 years of engineering experience, 10 of which in leading the development and operation of distributed software systems and cloud-native platforms.
  • Proficient in infrastructure-as-code design and tools such as Terraform.
  • Deep knowledge and experience in design patterns, implementation, testing, and failure management of distributed systems and microservices.
  • Hands-on experience with cloud-native software development and operations approach; primarily using tools and technologies such as Docker, Kubernetes, and Cloud services to run software services and data analytics jobs.
  • Proficient in industry security standards such as NIST CSF / SSDF with hands-on experience implementing and monitoring cloud security controls.
  • Experience with various code flow and DevOps approaches such as gitOps.
  • Experience in healthcare and life sciences especially developing medical devices is a big plus.
  • Personal Qualifications :

    We want to add a humble, curious, and collaborative member to our team. At the Karius engineering team, we highly value deep domain expertise, drive for innovation, desire to collaborate, being open to learning and unlearning, and passion for solving hard problems with a meaningful impact on the world.

    Disclaimer : The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required.

    Equal Opportunity Employer : At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.

    Salary : $210,000 - $290,000 a year

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    Salary : $210,000 - $290,000

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