What are the responsibilities and job description for the Scientist III position at Katalyst CRO?
Job Description
Biologics Developability Screening and Automation
The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development organization at Client. The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development. We have an exciting opportunity for a motivated scientist to join the Client Biologics CMC Developability team based in Worcester, MA.
Responsibilities
Biologics Developability Screening and Automation
The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development organization at Client. The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development. We have an exciting opportunity for a motivated scientist to join the Client Biologics CMC Developability team based in Worcester, MA.
Responsibilities
- Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post-translational modifications.
- Conduct biophysical and biochemical characterization of biologic drug candidates, as needed.
- Execute experimental protocols, collect results, and perform data analysis carefully and independently.
- Maintain excellent documentation of work including electronic lab notebook and protocols.
- Prepare and deliver concise scientific presentations of experimental results.
- Oversee maintenance of key laboratory equipment and routine laboratory operations.
- Build strong relationships with other team members and across groups.
- Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance.
- BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5 (BS) or 2 years (MS), or Ph.D. with 0 years of biopharmaceutical industry experience.
- Hands-on experience with protein mass-spectrometry (subunit analysis, peptide mapping, disulfide mapping).
- Experience with biochemical and biophysical characterization of biologic proteins would be preferred.
- Experience with liquid handling robots and their programming would be highly beneficial.
- Demonstrated track record of independent thinking, creativity, and scientific accomplishment.
- Highly responsible and self-motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel & GraphPad.
- Team player with excellent collaboration and communication skills.
