Senior Research Associate, Process Development

Landmark Bio translates groundbreaking research into life-changing medicines. We provide development, manufacturing, and regulatory capabilities to help early-stage life science innovators rapidly progress advanced therapies from bench to clinic. Launched in 2021, and based in Watertown, Mass. Landmark Bio is an unprecedented venture bringing together the best of industry, academia and research hospitals to accelerate life sciences innovation. 

We are seeking a highly motivated and team-oriented professional with entrepreneurial spirit to join our company! This is an exciting opportunity for a well-qualified candidate to join a rapidly growing company focused on turning today’s cutting-edge research into tomorrow’s breakthrough therapies.

We are seeking a Senior Research Associate, Process Development, responsible for executing cell culture experiments, downstream processing, analyzing data, and contributing to process development projects. The ideal candidate will be involved in troubleshooting complex issues. The position requires a strong understanding of all aspects of mammalian cell culture and aseptic technique, the ability to use small-scale bioreactors and purification principles, and experience with data analysis and scientific writing. This is a hands-on lab-based position requiring a flexible schedule based on experimental work; some weekend work may be required.

Responsibilities:      

·       Culturing and purifying different cell types including iPSC and MSC cells.

·       Maintain small-scale bioreactors from 0.5mL to 10L scale.

·       Cell transfection, transduction, and other genetic manipulation techniques. 

·       Use of purification techniques such as affinity and anion exchange chromatography and filtration-based unit operations.

·       Performance of general laboratory tasks, including maintenance of equipment.

·       Maintain accurate and reliable records including database management, batch records, lab notebooks, and all other pertinent documentation.

·       Write and/or contribute to SOPs, batch records, protocols and reports.

·       Comply with all safety and infection control standards.

Qualifications:

·       Bachelor’s degree in biology, bioengineering, biotechnology, or related discipline with minimum 2 years relevant experience.

·       Strong understanding of tissue culture and aseptic technique.

·       Willingness to work with different viral vector systems (lentiviral and AAV) and biological samples.

·       Strong team worker who is also independently motivated, detail oriented, with good problem-solving capabilities.

·       Strong verbal and written skills; able to handle confidential information and material appropriately.

·       Background in bioreactors and/or cell-based methods preferred.

Landmark Bio is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.