What are the responsibilities and job description for the Scientist/Sr. Scientist/ Principal Scientist position at Leal Therapeutics?
Leal Therapeutics is hiring a highly driven
Research Scientist / Sr. Scientist to join its Nucleic Acid Therapeutics Development team
in Worcester, MA location. This position will be responsible for overseeing screening and optimization of antibody oligonucleotide conjugate (AOC) compounds for therapeutic and platform projects.
About Leal Therapeutics :
Biotechnology company developing novel, precision therapeutics for major diseases of the central nervous system (CNS) with critical unmet needs including ALS, Schizophrenia, and Alzheimer's disease
Fast-paced startup environment with broad exposure to multiple facets of biotechnology and drug development
Emphasis on cross-functional collaboration within a collegial, learning-oriented environment
Continuous career development opportunities and support
Ability to have a large impact in a rapidly growing company
Key Responsibilities :
Provide expert leadership in the
process development of antibodies and AOCs, overseeing both strategic and day-to-day activities.
Responsible for providing subject-matter expertise in the design and construction of antibodies and AOC to support ongoing programs.
Engage with global partners in antibody and AOC co-development to support joint ventures, ensuring successful integration of process development strategies.
Hands-on experience with molecular biology and protein techniques including, but not limited to, ELISAs, Western blots, protein purification, qPCR, required
Experience with
in vivo
tissue handling, tissue homogenization and RNA isolation is preferred
Experience in bioanalysis of nucleic acids or proteins using hybridization ELISA or LC-MS is preferred
Education, Experience, and Qualities Required :
Ph.D. or MS in a relevant scientific discipline with 2-5 years additional experience required
- Experience in Antibody molecular biology required. Experience in nucleic acids preferred.
Strong laboratory skills and high degree of attention to detail
Strong problem-solving and troubleshooting skills
Excellent verbal and written communication skills
Ability to work collaboratively in a fast-paced, dynamic environment required
Passion for bringing new therapies to serve patients with unmet medical needs