What are the responsibilities and job description for the In Vivo Scientist II position at Legend Biotech US?
Company Information
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a In Vivo Scientist II as part of the Early Drug Development team based in Philadelphia, PA.
Role Overview
This position will perform preclinical in vivo pharmacology and toxicology studies to support pipeline programs. The ideal candidate will have experience in immunology or immune-oncology and in vivo studies with mouse and NHP to assist preclinical cell therapy studies from discovery to first-in-human trials. The successful candidate will work in a collaborative environment and would be skillful in driving multiple projects by contributing to the development of cell-based immunotherapies.
Key Responsibilities
- Conduct in vivo studies with mice and NHP; Interact with CROs for in vivo study related activities
- Interact with research teams for collaboration
- Process and analysis of tumor samples and tissues from mice and NHP
- Analyze, summary, review and present data
- Participate in assay development and qualification
- Maintain good documentation in ELN, paper notebook and log books.
- Perform additional exploratory and investigational studies with various techniques.
Requirements
- Ph.D. or Master degree in biological sciences (Immunology, cell biology and cancer biology) or related area is required
- Extensive hands-on in vivo study experience is required (2 years. Expertise in various injection, bleeding, tissue collection and processing).
- Extensive experience in execution of cell-based and multi-color flow cytometry methods required.
- Prior experience in CAR-T/NK cell therapy development preferred.
- Strong critical thinking and problem-solving skills
- Sense of ownership and integrity of their work.
- A demonstrated ability to work as part of a team
- Demonstrated organizational skills including but not limited to attention to detail and multitasking
- Biotech or pharmaceutical industry experience is preferred but not required.
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Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
Legend Biotech maintains a drug-free workplace.
