Post-Baccalaureate, Biology

At Lyterian Therapeutics, we are committed to developing medicines for patients in need by co-opting physiologically-relevant protein homeostatic mechanisms to regulate genetically-validated targets.

Position Summary:

As a Post-Baccalaureate in Biology you will be responsible for executing primary cellular screens to enable identification of lead molecules for our early drug discovery programs. In addition, you will assist in maintaining cell lines and preparing compound solutions for testing. By collaborating closely with a diverse team of scientists, you will help define the fundamental biology behind chemically modulating protein homeostasis.

We look for team members who are inspired by our mission and want to work in a collaborative, rigorous, and entrepreneurial environment. We seek colleagues who are self-motivated, innovative, proactive, and possess an innate curiosity to discover novel biology and new drugs. Efficient time management, excellent organizational and communication skills, and passion for high-quality, translational science are essential.

We offer:

As a post-baccalaureate (6–12-month appointment), we are seeking individuals looking to take a gap year between undergraduate education and the pursuit of an advanced degree (MS, PhD, MD, etc.). In this position you will gain invaluable experience in how the drug discovery and development process works at a start-up company. The successful candidate will be exposed to internal seminars focused on techniques, projects, and leveraging data for downstream decision-making. In addition, your supervisor will help you coordinate informational interviews with their extended network so that you acquire a more in-depth picture and understanding of requirements for advanced degrees at various institutions.

• Gain hands-on knowledge and experience in the design and execution of high-throughput screening leveraging fluorescence and luminescence detection platforms, high-content microscopy, and/or flow cytometry
• Optimize and run medium to high-throughput cellular screening assays, including compound solubilization and plate preparation
• Create, maintain, and utilize a variety of cell lines
• Register cell lines in an internal database
• Record experimental data in Electronic Lab Notebooks to ensure good record-keeping
• Present experimental work at cross-functional program team meetings
• Collaborate and communicate across a diverse scientific team to successfully progress Lyterian goals

• BA/BS in biology, biochemistry, molecular biology, or related discipline with 0-1 years of relevant experience
• Knowledge of basic wet lab techniques, molecular biology techniques, and tissue culture
• Prior experience in a lab setting (undergraduate research, internship, etc.) is required
• Ability to keep a detailed and organized lab notebook with records of experimental protocols and results
• Ability to prioritize and manage multiple tasks efficiently, communicate clearly, and work with multidisciplinary project teams
• An interest in understanding biochemical and cellular mechanisms, experimental design and assay development related to protein homeostasis drug discovery

At Lyterian, we believe that a diverse, open, and inclusive environment and culture is key to our success.  We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. Lyterian will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws.

Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.

Salary : $75,000 - $90,000