Demo

Principal Engineer, Fermentation Process Development

Manus
Augusta, GA Full Time
POSTED ON 2/9/2025
AVAILABLE BEFORE 5/8/2025

Job Description

Job Description

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a motivated individual for a Principal Engineer, Fermentation Process Development position to develop and optimize fermentation processes across bench and pilot-scale for multiple bioalternative products. This candidate will play an integral role as part of Manus’ process development team at our Augusta BioFacility.

Why work at Manus Bio :

  • Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities :

  • Develop, test, and optimize fermentation conditions and parameters for the production of complex natural products.
  • Apply knowledge of microbial physiology, biochemistry, metabolism, and process development to improve titer, yield, and productivity of engineered strains in fermentation.
  • Ensure that process development outcomes deliver against targeted commercial metrics and milestones.
  • Facilitate the transfer of technology and processes developed in the lab to pilot and commercial manufacturing
  • Stay abreast of industry trends, emerging technologies, and regulatory requirements in the bioprocessing field, and apply this knowledge to enhance processes and drive innovation
  • Work collaboratively with the Boston R&D team to evaluate strains and provide feedback
  • Communicate plans and experimental results with various technical teams
  • Required Qualifications :

  • Ph.D. in Bioengineering, Chemical Engineering, Biochemistry, Microbiology, or a related field with 2 or more years of industrial experience
  • Expertise in bench and pilot-scale fermentation process development
  • Expertise in microbial physiology
  • Critical thinker with enthusiasm for deriving solutions to complex challenges
  • Preferred Qualifications :

  • Experience with analytical instrumentation (GC, LC)
  • Experience in scale-up of fermentation processes from lab-scale to pilot plant and / or production-scale
  • Preferred Working Style :

  • Must be fully responsible and accountable for compliance with the provision of the safety,
  • health, and environmental (SHE) policies.

  • Must be very well-organized and be able to handle multiple projects simultaneously.
  • Must be a quick learner who is self-motivated and able to ask questions and seek clarity.
  • Must be flexible with day-to-day duties and able to thrive in a start-up environment.
  • Must be an excellent team member with strong communication skills and a desire to work
  • collaboratively.

  • Must hold themselves to the highest professional, scientific and ethical standards.
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