What are the responsibilities and job description for the Research Associate, CMC Radiochemistry position at Mariana Oncology?
Description:
We are seeking an experienced Research Associate, CMC Radiochemistry to join Marianas CMC organization, advancing personalized medicine and radiopharmaceuticals.
Illustrative Breadth of Responsibilities:
Implement and perform new and/or routine radiochemistry procedures and protocols under the direction of the CMC team
Investigate, analyze, and reach preliminary scientific conclusions related to research planning
Ensure data results are compiled, analyzed, and presented properly
Analyze, develop, interpret, and maintain clear documentation of scientific results
Prepare scientific reports for internal reporting purposes
Perform independent research and laboratory techniques and participate in experimental research planning
Opportunity to engage in early drug product formulation feasibility process development and analytical methodologies
Opportunity to learn radiolabeling/ coordination chemistry process, analytical development and troubleshooting with a broad range of radioisotopes, including but not limited to: Lu-177, Ac-225, Zr-89, Cu-64, In-111, Ga-68 and Pb-212
Participate in the development and process validation of radiopharmaceutical production procedures for use in preclinical and clinical studies
Participate and support CMC process and analytical development, method validation, and reporting activities
Support team communications in disseminating the results, which may come in the form of writing reports, presenting at internal meetings
Contribute to the organization, safety, and maintenance of the laboratory
Requirements/Skills:
A BS degree in Chemistry, Radiochemistry, or related discipline with 0-2 years of Biotech, Pharmaceutical, and/or PET industry experience in relevant biologics and peptides metal chelates chemistry development.
Knowledge of GMP is a plus
Radiopharmaceutical drug substance and drug product development experience and quality control is a plus
Analytical chemistry, specifically HPLC analysis
Working with radiopharmaceuticals, with a good understanding of the radiation safety regulations and guidelines, is preferred
Proven ability to adhere to good documentation standards and maintain detailed records of all work performed
Excellent verbal and written communication skills
Mariana Oncologys Principles
Building a Legacy
Execution Excellence
Courage of our Convictions
