Pre-Doctoral Fellow - Otobiomechanics

Site: Massachusetts Eye and Ear Infirmary

At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.

At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply.

Job Summary

POSITION SUMMARY:

Proposes and undertakes a mentored, innovative project or challenge to develop novel molecular therapies for inner ear degenerative diseases. Designs and performs in vitro and animal experiments, analyzes and presents the outcome.

ESSENTIAL FUNCTIONS:

Read, analyze and summarize published literature
Design and execute retrospective research studies
Assist in executing prospective research studies
Undertake relevant coursework if required by mentor.
Attend relevant meetings
Meet regularly with mentor to review project progress and milestones
Plan and deliver a seminar on the project
Take administrative (inventory, purchasing, etc. ) responsibilities in the lab when necessary
Write a final report or submit a manuscript to a peer-reviewed journal describing the project and results
Prepares basic solutions and performs base-level procedures as assigned (i.e. pipetting, cell and tissue culture, etc.).
Maintains laboratory notebook.
Understands molarity.
Conducts analysis of results and may begin interpretation of results.
Sets up and prepares routine experiments as directed.
Prepares lab reagents, chemicals, instruments, and equipment.
May perform independent literature searches.
Assists with organizing materials for publication or presentation.
Maintains and orders supplies.
May provide responsible care to animals.
Executes protocols of non-routine experiments.
Assists PI with determining the most suitable methodology.
Performs basic design and modification of protocols.
Calculates, transcribes, and analyzes data.
Prepares and presents reports.
Organizes and summarizes acquired data, using scientific and statistical techniques.
Organizes and/or drafts material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation.
Participates in the design of experiments or field work
Basic understanding of molecular biology techniques, genotyping.
Performing molecular biology including recombinant cloning and preparation of expression vectors
Performing transient transfections, selections, clone isolation and other standard molecular biology techniques

COMPETENCIES REQUIRED
Ability to work independently and as team member
Analytical skills and ability to resolve technical problems
Ability to interpret acceptability of data results
Working knowledge of data management programs
High Degree of computer literacy
Demonstrated competence in research techniques and methodologies.

SUPERVISION RECEIVED
Works independently with some supervision.
Supervisor available to handle unusual situations and periodically reviews work.
Lab peers available to teach new techniques

SUPERVISORY RESPONSIBILITIES
May serve as a team leader to undergraduate researchers, lab assistants and interns

EDUCATION AND EXPERIENCE:
Bachelor’s degree, pursuing a master’s or doctoral degree (MD or PhD) and with prior research experience. Minimum of 1 year of directly related experience.

WORKING CONDITIONS:
In-person in a laboratory setting and remotely (when possible).

PHYSICAL REQUIREMENTS:
Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s).

POSITION SUMMARY:

Proposes and undertakes a mentored, innovative project or challenge to develop novel molecular therapies for inner ear degenerative diseases. Designs and performs in vitro and animal experiments, analyzes and presents the outcome.

ESSENTIAL FUNCTIONS:

• Read, analyze and summarize published literature
• Design and execute retrospective research studies
• Assist in executing prospective research studies
• Undertake relevant coursework if required by mentor.
• Attend relevant meetings
• Meet regularly with mentor to review project progress and milestones
• Plan and deliver a seminar on the project
• Take administrative (inventory, purchasing, etc. ) responsibilities in the lab when necessary
• Write a final report or submit a manuscript to a peer-reviewed journal describing the project and results
• Prepares basic solutions and performs base-level procedures as assigned (i.e. pipetting, cell and tissue culture, etc.).
• Maintains laboratory notebook.
• Understands molarity.
• Conducts analysis of results and may begin interpretation of results.
• Sets up and prepares routine experiments as directed.
• Prepares lab reagents, chemicals, instruments, and equipment.
• May perform independent literature searches.
• Assists with organizing materials for publication or presentation.
• Maintains and orders supplies.
• May provide responsible care to animals.
• Executes protocols of non-routine experiments.
• Assists PI with determining the most suitable methodology.
• Performs basic design and modification of protocols.
• Calculates, transcribes, and analyzes data.
• Prepares and presents reports.
• Organizes and summarizes acquired data, using scientific and statistical techniques.
• Organizes and/or drafts material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation.
• Participates in the design of experiments or field work
• Basic understanding of molecular biology techniques, genotyping.
• Performing molecular biology including recombinant cloning and preparation of expression vectors
Performing transient transfections, selections, clone isolation and other standard molecular biology techniques

COMPETENCIES REQUIRED

• Ability to work independently and as team member
• Analytical skills and ability to resolve technical problems
• Ability to interpret acceptability of data results
• Working knowledge of data management programs
• High Degree of computer literacy
Demonstrated competence in research techniques and methodologies.

SUPERVISION RECEIVED

• Works independently with some supervision.
• Supervisor available to handle unusual situations and periodically reviews work.
Lab peers available to teach new techniques

SUPERVISORY RESPONSIBILITIES

May serve as a team leader to undergraduate researchers, lab assistants and interns

EDUCATION AND EXPERIENCE:

Bachelor’s degree, pursuing a master’s or doctoral degree (MD or PhD) and with prior research experience. Minimum of 1 year of directly related experience.

WORKING CONDITIONS:

In-person in a laboratory setting and remotely (when possible).

PHYSICAL REQUIREMENTS:

Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s).

Onsite

243-245 Charles Street

40

Regular

Day (United States of America)

Massachusetts Eye and Ear Infirmary is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.