What are the responsibilities and job description for the Director, Medical Science Liaison position at Maze Therapeutics?
The Position :
Are you passionate about building meaningful relationships with healthcare professionals and shaping the future of patient care? As a Director, Medical Science Liaison (MSL) on our Clinical Science team, you will play a key role in engaging external experts, supporting clinical programs, and shaping medical affairs strategy. Your work will directly impact Maze’s mission to develop treatments for APOL1 kidney disease, other chronic kidney diseases, and phenylketonuria (PKU) —areas with significant unmet medical need.
In this role, you’ll collaborate closely with healthcare providers, patient advocacy groups, and professional societies, ensuring our programs align with the latest advancements in the field. You’ll also provide valuable clinical insights that help shape our broader strategy, working alongside cross-functional teams in a fast-paced, mission-driven environment.
The Impact You’ll Have
- Build and maintain peer-to-peer relationships with key external experts in nephrology, inborn errors of metabolism, and related areas through in-person and virtual interactions.
- Support clinical trial execution by assisting with site selection, investigator training, trial recruitment, and ongoing site engagement.
- Partner with Maze’s patient advocacy team to cultivate relationships with patient advocacy groups and support scientific outreach and education efforts
- Identify areas of strategic collaboration , by developing relationships with professional societies to stay ahead of emerging trends.
- Gather and share clinical insights with internal teams to help shape drug development, scientific communications, and strategic initiatives.
- Develop and execute tactical plans to support Maze’s programs and align with broader company objectives
- Support scientific exchange and education with advisory boards, medical congresses, and data presentations
- Maintain compliance with all regulatory guidelines while ensuring clear and effective communication across stakeholders.
As a Director, we also expect our leaders to demonstrate the following Leadership Competencies :
Role models clear communication and open two-way conversations.
Champions collaborations and connections across Maze.
Develops recommendations to seize on opportunities and mitigate obstacles that could impact long-term success.
Develops staff capabilities to handle delegation of responsibilities.
What We’re Looking For
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $227,000 to $277,000. Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
Salary : $227,000 - $277,000
