Demo

Statistical Genetics Intern

Maze Therapeutics
Maze Therapeutics Salary
South San Francisco, CA Intern
POSTED ON 1/22/2025
AVAILABLE BEFORE 4/19/2025

The Program

Maze Therapeutics offers a dynamic 9-week summer internship program designed to provide hands-on experience and professional growth opportunities. As an intern, you’ll take ownership of impactful projects, gaining practical insights and learning from Maze employees. You will participate in several events and trainings with your fellow interns, including professional development workshops and discussions with Maze executive leaders. The program culminates with a company-wide presentation, where you’ll share your work and celebrate your achievements. This immersive experience will allow you to contribute to innovative research, grow professionally, and explore career paths within the biotechnology industry.

The Position

We are seeking an exceptional statistical geneticist in training to join our early research team as a Summer Intern. In this role, you will contribute to the design and execution of genetic association studies for both common and rare variants using large-scale genetic datasets. You’ll have the opportunity to integrate functional genomics data with human genetics findings to help identify novel therapeutic targets. Your work will directly support the development of disease-modifying therapies, collaborating closely with biologists and data scientists to advance Maze’s mission of developing precision medicines.

This is a unique opportunity to apply cutting-edge statistical genetics techniques, expand your understanding of drug discovery, and gain exposure to a multidisciplinary research environment.

How You’ll Contribute

  • Collaborate with your mentor in Human Genetics, working closely with the Data Science and Functional Genomics teams.
  • Perform human genetic analyses using large-scale whole genome sequencing (WGS) data to identify genetic associations with diseases.
  • Analyze longitudinal phenotype data to better understand disease progression and response to treatments.
  • Integrate human genetic data with functional genomics screens to prioritize therapeutic targets.
  • Present your findings to scientific teams and contribute to discussions on target discovery and validation.

What We’re Looking For

  • Education and Background :
  • Currently pursuing or recently completed a B.A. or B.S. in Genetics, Bioinformatics, Computational Biology, or a related field (Master’s or Ph.D. candidates are welcome to apply).

  • Strong understanding of GWAS (genome-wide association studies) and gene burden testing.
  • Familiarity with longitudinal data and electronic medical record data is highly recommended.
  • Technical Skills :
  • Experience with large-scale genetic datasets and a proven ability to analyze and interpret genomic associations.

  • Proficiency in R and experience with other tools commonly used to analyze genetic data.
  • Experience with version control systems (e.g., Git) and AWS cluster computing is a plus.
  • Key Attributes :
  • Strong analytical skills with a solid computational / statistical background.

  • Excellent communication skills to present your findings clearly to both technical and non-technical audiences.
  • A curious, motivated, and collaborative mindset with a desire to push scientific boundaries.
  • About Maze Therapeutics

    Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. We are advancing a pipeline using our Compass platform, which allows us to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process we refer to as variant functionalization. Our Compass platform has been purpose-built to inform all phases of our drug discovery and development process through clinical trial design. We are currently advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease, or CKD. Our goal is to bring novel precision medicines to patients with common diseases, which is where we believe we can maximize our impact on human health.

    Our People

    Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.

    Our Core Values

    Further Together  – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.

    Impact Obsessed  – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

    Stand True  – Our integrity is foundational; it guides us no matter the obstacle.

    The internship is scheduled to commence on June 16, 2025, and will conclude on August 15, 2025 (with potential flexibility in dates).

    The expected hourly rate for this role is as follows :

    Undergraduate : $28.00 / hour

    Graduate : $35.00 / hour

    Salary : $28 - $35

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