What are the responsibilities and job description for the Postdoctoral Fellow, FT, Temporary position at MBL New Logo?
Description: A position for a postdoctoral fellow is available in the Rosenthal laboratory of the Bell Center. Studies from the Rosenthal lab have shown that mRNA recoding by adenosine deamination is particularly active in the cephalopod nervous system (Alon et al. eLife 2015; Liscovitch-Brauer et al. Cell 2017; Vallecillo-Viejo et al. NAR, 2020). We are interested in exploring the molecular mechanisms underlying this process. This position will take advantage of newly developed protocols for CRISPR-Cas9 based genome editing in cephalopods to explore the relationship between the novel features of squid RNA editing enzymes (ADARs) and high-level mRNA recoding. We are searching for an applicant with strong skills in designing and implementing experiments across on cephalopod ADARs. This work, supported by the MBL’s cephalopod program, will provide a unique opportunity to study genetically tractable cephalopods. The project is in collaboration with Dr. Eli Eisenberg, a bioinformatics expert, from Tel Aviv University.
Duties. The postdoc will be expected analyze data related to CRISPR-Cas9 ADAR1 knockouts in Euprymna berryi and specifically explore changes in RNA editing at the molecular level, and phenotypic changes at the developmental and physiological levels. In addition, responsibilities will include finalizing a manuscript describing the ADAR1 knockouts. The postdoc will be expected to demonstrate independence and a strong work ethic. An in-depth understanding of cephalopod RNA editing and molecular biological bench techniques is required. Experience working with Illumina data is desirable. Experience working with cephalopods, is also required. The successful candidate will need to work closely with members of the Rosenthal laboratory, the MBL’s cephalopod husbandry team, and Eli Eisenberg, a collaborator on this project at Tel Aviv University.
Conditions: This position is for two months (7/1/25 - 8/31/25) without the possibility for extension.
Education: EDUCATIONAL/EXPERIENCE/SKILLS: A PhD degree (or equivalent) in biological sciences or a closely related field and 3 years postdoctoral experience working with cephalopods. Previous experience in molecular biology is required. Experience with genome editing and/or bioinformatics skills related to RNAseq is also required.
