What are the responsibilities and job description for the Associate Director, Disease & Molecular Pathways position at Merck?
Job Description
The Precision Genetics group within the Data and Genome Sciences Department is seeking an Associate Principal Scientist/Associate Director to join our Disease and Molecular Pathways team in Cambridge, MA. We are looking for a skilled data scientist with extensive experience in multi-modal and multi-scale data analysis to advance our understanding of disease mechanisms.
Key Responsibilities
Current Contingent Workers apply HERE
US And Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
About
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status
Regular
Relocation:
Domestic
VISA Sponsorship
Yes
Travel Requirements
10%
Flexible Work Arrangements
Hybrid
Shift
Not Indicated
Valid Driving License
No
Hazardous Material(s)
n/a
Required Skills
Data Science, High Performance Computing (HPC), Machine Learning, Researching, Scientific Modeling
Preferred Skills
Job Posting End Date:
03/10/2025
The Precision Genetics group within the Data and Genome Sciences Department is seeking an Associate Principal Scientist/Associate Director to join our Disease and Molecular Pathways team in Cambridge, MA. We are looking for a skilled data scientist with extensive experience in multi-modal and multi-scale data analysis to advance our understanding of disease mechanisms.
Key Responsibilities
- Data Set Identification: Proactively identify relevant datasets from public, internal, and proprietary sources through collaborative efforts.
- Collaborative Research: Partner closely with Statistical Geneticists, AI/ML scientists, and disease area biologists to develop tailored analytical strategies for complex diseases across various therapeutic areas.
- Strategic Partnership: Serve as a strategic collaborator with discovery teams to influence the drug discovery portfolio.
- Hands-On Analysis: Implement rigorous data analysis practices and remain informed about cutting-edge computational approaches.
- Multi-Modal Data Analysis: Analyze diverse data types to generate hypotheses related to targets and biomarkers across therapeutic areas.
- Causal Biology Exploration: Utilize advanced machine learning techniques to establish causal relationships in biological systems.
- Spatial Transcriptomics: Collaborate with the Genome Sciences group to perform spatial transcriptomics on patient-derived samples.
- Emerging Methods: Stay at the forefront of novel methodologies in computational biology.
- Project Management: Manage complex projects, proactively identifying challenges and forecasting timelines for key deliverables to meet pipeline objectives.
- Validation Collaboration: Work with wet-lab biologists and disease area experts to validate disease mechanisms and identify patient sub-populations.
- Effective Communication: Present findings to project teams, internal stakeholders, and the broader scientific community through internal documentation, presentations, and publications in leading journals.
- Ph.D. in Computational Biology or a related field, with a minimum of 5 years of post-PhD research experience.
- Proven track record of over 5 years in multi-omic data integration for target discovery.
- Fundamental knowledge of statistical and population genetics principles.
- Strong conceptual understanding of common statistical techniques, including regression, dimensionality reduction, network analysis, and data harmonization.
- Proficiency in coding using R and Python, with the ability to establish best practices for reproducible data analyses.
- Exceptional skills in navigating and influencing within complex, matrixed organizations.
- Excellent written and verbal communication skills.
- Experience in fields such as Neuroscience, Cardiovascular and Metabolic diseases, Immunology, or other complex diseases.
- Familiarity with integrating single-cell transcriptomics and human genetics.
Current Contingent Workers apply HERE
US And Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
About
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status
Regular
Relocation:
Domestic
VISA Sponsorship
Yes
Travel Requirements
10%
Flexible Work Arrangements
Hybrid
Shift
Not Indicated
Valid Driving License
No
Hazardous Material(s)
n/a
Required Skills
Data Science, High Performance Computing (HPC), Machine Learning, Researching, Scientific Modeling
Preferred Skills
Job Posting End Date:
03/10/2025
- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
