What are the responsibilities and job description for the Senior Principal Scientist, Translational Medicine, Vaccines position at Merck?
Translational Medicine in our Research & Development Division is responsible for planning and management of an important inflection point in the drug development process, working closely with scientific, regulatory, statistical, and modelling colleagues across the organization to translate the benchtop science of preclinical discovery into compounds ready for assessment in large clinical populations.
We are seeking a highly qualified physician-scientist with a proven track record in the pharmaceutical industry as well as independent academic research for a position in our group.
The preferred candidate will have at least 5-year experience in the pharmaceutical industry and Vaccine and Infectious Diseases R&D and clinical and academic expertise in vaccine-related areas such as Infectious Diseases / Pediatrics, Preventative Medicine / Immunology / Microbiology.
For our efforts supporting the vaccine development pipeline, our closest collaborations are with groups based in West Point PA, Upper Gwynned, PA, Rahway, NJ, Boston MA and San Francisco, CA.
Translational Medicine is specifically responsible for :
- Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical insight into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in full development.
- Development of biomarker strategies through cross-functional teams that provide line-of-sight from First-in-Human studies through clinical Proof-of-Concept. This includes Experimental Medicine studies to establish and / or validate novel clinical biomarker platforms.
- Development and execution of the early clinical development strategy for novel therapy / vaccine programs from Preclinical Candidate approval through clinical Proof-of-Concept (Phase 2a), and development and execution of clinical pharmacology strategies for late-stage development programs from Proof-of-Concept (Phase 2a) through worldwide marketing application.
Success depends on the integrity, knowledge, imagination, creativity, skill, diversity, and teamwork of the people in the group. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of the global team, you will collaborate with talented and dedicated colleagues in Translational Medicine, as well as Discovery Sciences and late-stage Clinical Research while developing and expanding your career.
This role will report directly to the Vaccine Therapeutic Area Lead in Translational Medicine.
Primary responsibilities for the Senior Principal Scientist include the following :
Position Qualifications :
Required Experience and Skills :
Current Employees apply HERE (https : / / wd5.myworkday.com / msd / d / task / 1422$6687.htmld)
Current Contingent Workers apply HERE (https : / / wd5.myworkday.com / msd / d / task / 1422$4020.htmld)
US and Puerto Rico Residents Only :
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.
Expected US salary range :
276,600.00 - $435,400.00
Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here (https : / / www.benefitsatmerck.com / ).
San Francisco Residents Only :
We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.
Los Angeles Residents Only :
We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status : Regular
Relocation : VISA Sponsorship :
Travel Requirements :
Flexible Work Arrangements :
Remote
Shift :
Valid Driving License :
Job Posting End Date :
02 / 2 / 2025
J-18808-Ljbffr
Salary : $276,600 - $435,400
