Scientist I, Protein & Structural Biology *PC 1455

Your Tasks:

This Scientist-I role is for those with demonstrated education, training, and/or work experience in protein engineering, computational structural biology, AI/ML, and its application in cell therapy, including CAR-T therapy, medicine, or a related field, as specified. The position reports to the group leader, and the duties include leading and assisting the group leader in executing projects and developing products in the cell and gene therapy area.

Essential Duties and Responsibilities:

• Conduct computational modeling and simulations of protein structures to predict their behavior and interactions.
• Analyze and interpret data using cutting-edge tools and software for protein structure prediction and design.
• Collaborate with experimental biologists to design new constructs and mutants based on structural analysis for all project progression and validation aspects.
• Maintain detailed laboratory notebooks and documentation of computational procedures and results.
• Present research findings in meetings, conferences, and published papers.
• Stay updated on current literature and advancements in protein engineering and computational biology.
• Participate in interdisciplinary team projects, contributing computational insights as a subject matter expert to overall research goals.
• Responsible for the development of computational methodologies and strategies in the analysis of proteins.
• Cross-functional collaborations between all sites globally.
• Assist in developing and maintaining databases for protein structures and related information.
• Utilize machine learning techniques for pattern recognition and predictive modeling in protein engineering.
• Provide computational training and support to lab members and collaborators.

Requirements: 

• Ph.D. Degree in (biochemistry, biochemical engineering, computational science); 0-2 years of relevant experience and/or training in structural biology, computational biology, immunology, cancer immunology, cell therapy, AI/ML in biology; Or a combination of education and experience. 
• Candidates from both industry and academia are welcome.
• Candidates with higher experience are encouraged to apply.  If selected, we will calibrate the level and title according to the years of relevant experience.
• Hands-on experience or a thorough understanding in any of the following areas is a plus: advanced Linux bash scripting, Python programming, pymol, docker, protein crystallography, cloning, protein expression, library design, protein characterization, assay design, cell culture.
• Experience in cutting-edge AI/ML technologies (such as ESM2, alphafold, novafold), protein modeling techniques is a plus.
• Strong verbal and written communication skills and ability to communicate results to a diverse cross-functional audience.
• Proactive, self-motivated team player with strong interpersonal skills, appropriate sense of urgency, and the ability to work independently.
• Ability to work in a fast-paced environment with a challenging workload and to quickly get acquainted with novel methods and approaches.
• Desire to advance knowledge in the scientific field through a consistent survey of new literature.

Physical Demands:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel; reach with hands and arms, talk and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 15lbs. Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail. Must be able to travel routinely by car and plane.

Work Environment:

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. This job is performed in a temperature-controlled facility without exposure to extreme hot or cold temperatures. Generally, this job is performed in a sanitized laboratory setting and routinely uses standard medical and research equipment such as centrifuges, biosafety cabinets, microscopes, incubators, pipettes and computers. While performing the duties of this job, the employee is frequently exposed to blood, viruses, bacteria, body fluids and other tissues. Employees entering and leaving the laboratory must wear appropriate clothing and protective equipment. The noise level in the work environment is usually moderate.

Miltenyi Biotec, Inc is an EO Employer – M/F/Veteran/Disability/Sexual Orientation/Gender Identity

Miltenyi Biotec, Inc. participates in E-Verify.

Are you ready to start revolutionizing biomedical research? When you join Miltenyi Biotec, you join a family that is passionate about making a real impact – one breakthrough at a time. One integral division of that Miltenyi Biotec family is Miltenyi Bioindustry — our contract development and manufacturing organization (CDMO). As a full-scale CDMO, we provide customers with services for the development and manufacturing of lentiviral vectors and cell and gene therapy products. This crucial arm of our enterprise bridges the gap between research and mass bioproduction, ensuring that our solutions are accessible on a global scale. Miltenyi Bioindustry plays a unique role as both the producer and the service provider, relying on our instruments and reagents for each workflow step, controlling the entire supply chain and thus delivering greater security and planning clarity to our customers.