Research Associate, in vivo pharmacology

Nilo Therapeutics is an early-stage biotech company developing groundbreaking therapies for autoimmune and inflammatory diseases. Our experienced team brings together diverse interdisciplinary expertise to modulate immune responses via activation of neural circuits. United by our passion for discovering and translating novel biology, we are dedicated to advancing human health through transformative science.

We are backed by The Column Group, Lux, and DCVC Bio.

Position

We are seeking a highly motivated (Senior) Research Associate to join our Biology / Therapeutics Team. The candidate for this position will be part of a team developing inflammatory animal models to assess the therapeutic potential of our platform and validate targets for a broad range of auto-immune diseases. We are seeking individuals with expertise in in vivo animal handling and dosing, plus training in molecular biology, cell biology and/or immunology.

Ideal candidates will use their scientific acumen and collaborative approach to partner across the interdisciplinary Nilo team on all aspects of the drug discovery process. This is an exciting opportunity to lead innovative research projects and make significant contributions to our mission of advancing therapeutic solutions.

At Nilo Therapeutics, we are a dynamic start-up at the forefront of biotech innovation, driven to discover novel biology and develop new drugs. We seek team members who are inspired by our mission and thrive in a collaborative, rigorous, and entrepreneurial environment. Ideal candidates are self-motivated, proactive problem solvers, excited to build and grow the company alongside a world-class team. If you are comfortable with managing multiple projects and possess a resourceful, can-do attitude, we would love to hear from you. Join us and contribute to our mission of advancing innovative therapies at the intersection of neuroscience and immunology.

What you’ll do:

• Collaboratively design and conduct in vivo acute and chronic experiments in rodents to evaluate targets using inflammatory disease models
• Demonstrate proficiency in primary cell culture, multi-color flow cytometry, ELISA, basic molecular biology and immune assays
• Perform H&E / immunofluorescence staining and confocal microscopy
• Perform in vivo rodent studies, including formulation, dosing, pharmacokinetic sampling, and necropsy
• Perform qPCR, ELISA and other common molecular biology/biochemistry techniques to advance research progress
• Collaborate cross-functionally with experts in Neuroscience, Bioinformatics, Drug Discovery and CROs to advance target identification and validation
• Independently prepare data and present to the team
• Work to improve existing animal protocols and implement solutions / troubleshoot as needed
• Maintain detailed and organized ELN records in accordance with company standards
• Assist with new technique or method development
• Collaborate cross-functionally with experts in Neuroscience, Immunology, Bioinformatics, and Drug Discovery to advance target identification and validation

Key Qualifications:

• BS/BA in cell biology, molecular biology, immunology or a relate discipline required
• 1-3 years of experience working in academic lab or industry is desired
• Ability to work atypical work hours (most weekends)
• Extensive hands-on experience working with rodents (experience in running chronic inflammatory disease models in mice is a plus)
• Experience working with small molecular and able to perform multiple routes of dose administration in rodents required (IP, PO, IV)
• Experience with cell biology or molecular biology techniques is a plus
• Excellent organizational and communication skills, with the ability to manage multiple projects and deadlines.
• Flexibility to learn new methods and skills for changing research priorities
• Proven ability to work collaboratively in a multidisciplinary team environment and motivated to make significant contributions for the growth of a high-paced start-up.
• A passion for high-quality, translational science and a desire to discover novel biology and new drugs

We offer a competitive compensation package that includes a range of benefits designed to support the well-being and professional growth of our team members.

For immediate consideration, please share your cover letter and resume with our hiring team.

Nilo Therapeutics is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment. We are committed to creating a diverse and inclusive environment and encourage individuals from all backgrounds to apply.