What are the responsibilities and job description for the Principal Scientist position at Nkarta Inc.?
About Us
Nkarta is a publicly traded ( Nasdaq symbol NKTX ), biotechnology company headquartered in South San Francisco focused on the discovery, development and manufacturing of off-the-shelf, natural killer (NK) cell therapies. Our near-term goal is to bring cell therapy out into the community setting, dramatically expanding access for patients.
Founded in 2015 at the birthplace of biotechnology, Nkarta is a fast-growing, fast-moving, clinical-stage company that has built an extensive cell therapy manufacturing operation in anticipation of product commercialization. Our developmental pipeline of engineered NK cell therapies includes clinical programs in B-cell malignancies and autoimmune diseases.
Complementing our broad research and development capabilities, Nkarta has also built an extensive cell therapy manufacturing operation. We recently built out a 23,000-square foot clinical good manufacturing practice, or cGMP, facility on-site at our primary corporate location in South San Francisco, California.
Nkarta is a people-driven company looking for passionate, collaborative, driven team members galvanized by a paradigm-shifting opportunity to change the cell therapy landscape.
Overview
Nkarta is seeking a highly motivated, collaborative, detail-oriented Principal Scientist to join our Translational Medicine team. The successful candidate will have expertise in immunology, immune cell therapy and / or autoimmune diseases. This individual will work independently and collaboratively within Translational Medicine and cross-functionally to advance and support biomarker assay development, MOA investigations and data analysis from clinical samples to support translational and clinical strategies in early development. This role is ideal for an individual who is driven and passionate about cell therapy for the treatment of hard-to-treat diseases.
Responsibilities
- Lead development of biomarker strategies and discovery with design, development and execution of experiments, validation, and transfer of assays to a third-party vendor.
- Lead translational research projects and design, plan, and execute experiments to support hypotheses that address high priority questions such as those related to clinical efficacy, MOA and immunogenicity.
- Collaborate with bioinformatics to implement and support functional genomic research using cutting-edge technology platforms.
- Perform in-depth scientific literature reviews on autoimmune disease biology and indications.
- Work independently; accurately record, analyze, and communicate data to senior staff and team members.
- Communicate results and data effectively in internal team and cross-functionally during company presentations and / or external scientific conferences.
- Collaborate with team members and serve as scientific mentor to Scientists and Research Associates.
Qualifications
Working at Nkarta Inc.
The common requirements of an office environment (computers, computer screens, workstations, etc.) apply when not working in or around the laboratory environment. Car and airplane travel might be required for this role for conferences and meetings. This role is local to the office in South San Francisco; however, the work hours are flexible as agreed upon.
A reasonable estimate of the current salary range for this position is $175,000 - $213,000. There are several factors taken into consideration in determining base salary, including but not limited to : job-related qualifications, skills, education and experience, as well as the value of other elements of an employee’s total compensation package. Nkarta also offers an annual discretionary bonus, equity grant(s), medical, dental, vision and life insurance coverage, in accordance with the terms and conditions of the applicable plans. Other benefits include 401K plan, flexible spending account, ESPP, employee assistance program, paid vacation, holiday and personal days, paid parental, pregnancy, and bereavement leave.
To learn more about our work at Nkarta and the career opportunities that will drive us forward to serve patients, please visit the company’s website at https : / / www.nkartatx.com .
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Salary : $175,000 - $213,000
