What are the responsibilities and job description for the Head of CADD (Computer-Aided Drug Discovery) position at Novartis?
20 million!
That’s the number of proprietary quantitative activity measurements available for data mining and modeling. As leader of the Computer-Aided Drug Discovery (CADD) team in Emeryville, CA, you will be able to leverage that knowledge-base, plus the knowledge-base of proprietary structural and pharmacological target information, to discover transformative drug candidates. In this key leadership position, you will have opportunities to explore the power of cutting-edge science and technology (e.g., cryoEM, VR, high performance computing) in an environment that truly values multidisciplinary collaborations
At the Novartis Institutes for BioMedical Research (NIBR), we value your ideas, personal growth, and career aspirations. We are a well-regarded research group that values engagement in the wider scientific community. In order to tackle the world’s toughest medical challenges, you will be empowered to take smart risks in an unbossed way, using your creativity and resourcefulness.
We are seeking a unique, experienced computational scientist to lead our team, operating in an interdisciplinary and tightly integrated site with local and global responsibilities. As part of the Emeryville Protein Interactomics Center, we contribute to drug discovery and technology developments across all research sites, disease areas, and technology platforms. We are also a strong local partner to the Novartis Institutes for Tropical Diseases, contributing to a pipeline of medicines for major global health challenges. In all our endeavors, we build on NIBR’s vast knowledgebase and the partnership and expertise of over 5,000 scientists with a huge variety of expert skills and a strong dedication to innovation.
As an insightful, collaborative, and decisive leader and innovator, you will bring strong cross-disciplinary knowledge and scientific leadership to motivate creative, curious scientists. Your scientific skills, experience and passion will lead the way to effectively explore chemical space and delve deep into molecular detail to discover transformative drug candidates.
The role is based out of our Bay Area location (Emeryville), but with a hybrid work model (office/home)
Primary Responsibilities:
That’s the number of proprietary quantitative activity measurements available for data mining and modeling. As leader of the Computer-Aided Drug Discovery (CADD) team in Emeryville, CA, you will be able to leverage that knowledge-base, plus the knowledge-base of proprietary structural and pharmacological target information, to discover transformative drug candidates. In this key leadership position, you will have opportunities to explore the power of cutting-edge science and technology (e.g., cryoEM, VR, high performance computing) in an environment that truly values multidisciplinary collaborations
At the Novartis Institutes for BioMedical Research (NIBR), we value your ideas, personal growth, and career aspirations. We are a well-regarded research group that values engagement in the wider scientific community. In order to tackle the world’s toughest medical challenges, you will be empowered to take smart risks in an unbossed way, using your creativity and resourcefulness.
We are seeking a unique, experienced computational scientist to lead our team, operating in an interdisciplinary and tightly integrated site with local and global responsibilities. As part of the Emeryville Protein Interactomics Center, we contribute to drug discovery and technology developments across all research sites, disease areas, and technology platforms. We are also a strong local partner to the Novartis Institutes for Tropical Diseases, contributing to a pipeline of medicines for major global health challenges. In all our endeavors, we build on NIBR’s vast knowledgebase and the partnership and expertise of over 5,000 scientists with a huge variety of expert skills and a strong dedication to innovation.
As an insightful, collaborative, and decisive leader and innovator, you will bring strong cross-disciplinary knowledge and scientific leadership to motivate creative, curious scientists. Your scientific skills, experience and passion will lead the way to effectively explore chemical space and delve deep into molecular detail to discover transformative drug candidates.
The role is based out of our Bay Area location (Emeryville), but with a hybrid work model (office/home)
Primary Responsibilities:
- Conceive and lead research programs within the NIBR portfolio
- Develop and achieve long range program goals and drive their completion for several projects in parallel
- Bring hands-on experience to develop and apply innovative computational approaches to generate 3D structural understanding of the mechanism of action for novel ligands using advanced modeling and dynamics simulations in close collaboration with experimental scientists
- Engage and influence interdisciplinary project teams for effective decision-making from target identification through candidate nomination
- Identify, initiate, and conceptualize new practices to solve problems
- Set the strategy and direction of the med chem portfolio from early to late-stage and ensure delivery
- Support integration of new technologies to enhance scientific excellence and productivity
- Set the strategy and scientific direction across sites as part of our Global CADD leadership team; champion development and adoption of novel technologies, represent CADD and GDC internally and externally.
- Mentor and develop direct reports and other selected scientists (based on match of experience and topic of development)
- Provide guidance and feedback on issues of strategy, management, and performance to local and global teams
- Keep abreast of scientific developments and interact with internal and external scientists to integrate novel insights into computational approaches for drug discovery
EEO Statement
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Minimum requirements
Advanced degree in computational chemistry, computational biology, computational chemical biology, or related field
Why Consider Novartis?
We believe the answers are found when curious, courageous, and collaborative people like you are brought together in an inspiring environment—where you’re given opportunities to explore the power of digital and data, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.
We are Novartis. Join us to help reimagine medicine.
Apply now!
Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams, representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com or call 1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination.
As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to Eh.occupationalhealth@novartis.com.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
- 12 years of experience applying computational methods to drug discovery
- Hands-on experience with proven impact in several of the following CADD approaches: Structure-based Drug Design, Virtual Screening & Triaging, Hit and Lead Finding, Molecular Dynamics, Free Energy, Multi-Objective Optimization, Generative Chemistry
- Highly visible in the scientific drug discovery community: peer-reviewed publications, presentations at well-recognized venues
- Recognized leader with a track record of providing strategic direction, initiating projects, overcoming challenges, advancing science, and delivering for the drug discovery pipeline
- Experience in managing and developing scientists
Why Consider Novartis?
We believe the answers are found when curious, courageous, and collaborative people like you are brought together in an inspiring environment—where you’re given opportunities to explore the power of digital and data, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.
We are Novartis. Join us to help reimagine medicine.
Apply now!
Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams, representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com or call 1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination.
As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to Eh.occupationalhealth@novartis.com.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Division
NIBR
Business Unit
Global Discovery Chemistry
Country
USA
Work Location
Emeryville, CA
Company/Legal Entity
NIBRI
Functional Area
Data Science
Job Type
Full Time
Employment Type
Regular
Shift Work
No
Early Talent
No
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